Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cushing Disease: early-phase trial registry
7 of 9 indexed Cushing Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · 7 currently recruiting · #1,916 of 28,707 conditions by registered trial count
Cushing Disease: 9 US clinical trials tracked, 7 recruiting.
Cushing Disease is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), running 2 of these trials.
Enrollment posture brief
Registry condition cushing-disease
OPEN 7 | RECR 78% | LATE 1 | EARLY 4 | RANK #1916 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Advanced Colorectal Carcinoma (78% recruiting · 9 trials)
Cushing Disease lists 7 open slots (78% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cushing Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cushing Disease is recruiting above its size-band peers.
7 of 9 indexed trials (77.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Cushing Disease research.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) accounts for 2 of 9 trials (22.2%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Cushing Disease enrolment sits around 51 participants.
Median target enrolment is 51 among the 9 trials that report a genuine target (sentinel values excluded). 5 of those (55.6%) plan for fewer than 100 participants.
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Cushing Disease splits between interventional and observational designs.
5 interventional and 4 observational studies make up this index (55.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
9 total, page 1 of 1
An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00001595
Long-Term Follow-Up of Survivors of Pediatric Cushing Disease
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT03831958
Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Memorial Sloan Kettering Cancer Center
NCT03364803
Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors
Mayo Clinic
NCT07335315
Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease
University of California, Los Angeles
NCT05971758
A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
Crinetics Pharmaceuticals
NCT05804669
Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease
Cedars-Sinai Medical Center
NCT03774446
Open-label Treatment in Cushing's Syndrome
Cortendo AB
NCT03621280
Safety and Efficacy of LCI699 in Cushing's Disease Patients
Novartis Pharmaceuticals
NCT01331239
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Cushing Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cushing Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cushing Disease page
9 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 7 Cushing Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) sponsors the most Cushing Disease trials on record, review their full trial history before evaluating a specific study. See Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cushing Disease condition card totals 9 registered trials; most-linked intervention Levoketoconazole; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.