Crinetics Pharmaceuticals

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Crinetics Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#886 of 15,742 sponsors by registered trial count).

16 total trials 6 currently recruiting 6 completed early-phase tilt top decile by trial count

Crinetics Pharmaceuticals: 16 sponsored US clinical trials, 6 recruiting.

Crinetics Pharmaceuticals sponsors 16 registered US clinical trials on ClinicalTrials.gov, 6 of them currently recruiting, and 6 completed. 4 of these trials are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Classic Congenital Adrenal Hyperplasia, with 3 trials.

Top-decile sponsor footprint

Crinetics Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#886 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

16 total, page 1 of 1

RECRUITING Phase 2

A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

NCT07159841

RECRUITING Phase 3

A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia

NCT07144163

RECRUITING Phase 1

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

NCT07129252

RECRUITING Phase 3

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

NCT07087054

RECRUITING Phase 2

An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

NCT06712823

RECRUITING Phase 1

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

NCT05804669

ACTIVE NOT RECRUITING Phase 1

Drug-Drug Interaction Study of Atumelnant in Healthy Participants

NCT07570082

ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)

NCT05192382

ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly

NCT04837040

ACTIVE NOT RECRUITING Phase 2

A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)

NCT04261712

COMPLETED Phase 1

A Study to Assess Pharmacokinetics, Safety, and Tolerability of Atumelnant in Healthy Japanese and Caucasian Participants

NCT07221084

COMPLETED Phase 2

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

NCT05907291

COMPLETED Phase 2

Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome

NCT05361668

COMPLETED Phase 1

Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers

NCT06048887

COMPLETED Phase 2

An Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Edge)

NCT03789656

COMPLETED Phase 2

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Evolve)

NCT03792555

What is open in the Crinetics Pharmaceuticals pipeline

6 recruiting of 16 indexed (38% open); 6 completed (38%).

Phase mix: 4 late (III/IV) vs 12 early (I/II) (early-phase heavy).

Top condition: Classic Congenital Adrenal Hyperplasia (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Crinetics Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 16 registered trials and 38% open enrollment, not the therapeutic-area sidebar.

Crinetics Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 681012141618 0%10%20%30%40% Total trials Recruiting share Crinetics PharmaceuticalsAccelerated Community Oncology Research NetworkAltimmuneAmerican UniversityAnthera PharmaceuticalsAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)American Thrombosis and Hemostasis NetworkAskBioAthletic Greens International
Crinetics Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Crinetics Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 16 trials (± recruiting share)

Sponsors near 38% open enrollment (± trial volume)

What to do with this Crinetics Pharmaceuticals page

16 registered trials is a research-attention snapshot, not an endorsement of Crinetics Pharmaceuticals or any single study.

  • 6 of Crinetics Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Classic Congenital Adrenal Hyperplasia is the condition Crinetics Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Classic Congenital Adrenal Hyperplasia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Crinetics Pharmaceuticals pipeline card: 16 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.