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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Advanced Colorectal Carcinoma: early-phase trial registry

7 of 9 indexed Advanced Colorectal Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 7 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Advanced Colorectal Carcinoma: 9 US clinical trials tracked, 7 recruiting.

Advanced Colorectal Carcinoma is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 2 of these trials.

Enrollment posture brief

Registry condition advanced-colorectal-carcinoma

OPEN 7 | RECR 78% | LATE 0 | EARLY 7 | RANK #1916 | SPON 2

Nearest open-share peer: Cardiac Amyloidosis (78% recruiting · 9 trials)

Advanced Colorectal Carc (th…78%Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Advanced Colorectal Carcinoma

Advanced Colorectal Carcinoma lists 7 open slots (78% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Advanced Colorectal Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Advanced Colorectal Carcinoma is recruiting above its size-band peers.

    7 of 9 indexed trials (77.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Advanced Colorectal Carcinoma research.

    National Cancer Institute (NCI) accounts for 2 of 9 trials (22.2%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Advanced Colorectal Carcinoma enrolment sits around 94 participants.

    Median target enrolment is 94 among the 9 trials that report a genuine target (sentinel values excluded). 5 of those (55.6%) plan for fewer than 100 participants.

  4. Advanced Colorectal Carcinoma research is mostly interventional.

    8 interventional and 1 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 23

Open and recent trials

9 total, page 1 of 1

RECRUITING 800 participants

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

University of Rochester

NCT06073431

RECRUITING Phase 2 220 participants

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Mayo Clinic

NCT05969860

RECRUITING NA 190 participants

Engage Psychosocial Intervention for Cancer Symptoms

Duke University

NCT06555588

RECRUITING Phase 1 100 participants

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

University of California, Davis

NCT05967533

RECRUITING Phase 2 94 participants

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Northwestern University

NCT05733000

RECRUITING Phase 1 53 participants

A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

University of Chicago

NCT05200442

RECRUITING Phase 1 51 participants

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

National Cancer Institute (NCI)

NCT04704661

ACTIVE NOT RECRUITING Phase 2 39 participants

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

M.D. Anderson Cancer Center

NCT02983578

ACTIVE NOT RECRUITING Phase 1 10 participants

Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines

National Cancer Institute (NCI)

NCT04535401

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 3

Named interventions

Most-linked intervention names on Advanced Colorectal Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Biospecimen Collection Procedure
4 trials
Computed Tomography Procedure
3 trials
Fluorouracil Drug
2 trials
Elimusertib Drug
1 trials
Pill Diary Other
1 trials
VS-6766/avutometinib Drug
1 trials
Clinical Encounter Procedure
1 trials
Danvatirsen Drug
1 trials

US sites by state

Facility locations filed on Advanced Colorectal Carcinoma trials. A trial with sites in several states counts in each.

Illinois 3 trials
California 3 trials
Texas 2 trials
Pennsylvania 2 trials
New York 2 trials
Missouri 2 trials
Maryland 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Advanced Colorectal Carcinoma page

9 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Advanced Colorectal Carcinoma condition card totals 9 registered trials; most-linked intervention Biospecimen Collection; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.