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ClinicalTrials.gov 10 recruiting now official registry

CRC, Colorectal Cancer clinical trials

10 of 11 indexed CRC, Colorectal Cancer trials are currently recruiting.

11 US clinical trials · 10 currently recruiting

CRC, Colorectal Cancer is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is City of Hope Medical Center, running 2 of these trials.

The research picture

CRC, Colorectal Cancer has 11 registered US clinical trials, 10 of them open to new participants right now, about 91% of the total.

10
recruiting participants now
91%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: City of Hope Medical Center
Phase 16Phase 21Phase 31

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 3 700 participants

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Incyte Corporation

NCT07284849

RECRUITING 600 participants

cfDNA 5mC/5hmC Biomarkers to Predict Chemotherapy Response in Metastatic Colorectal Cancer

City of Hope Medical Center

NCT07224815

RECRUITING 500 participants

Development of a cfDNA 5mC/5hmC-based Biomarker Panel to Predict Targeted Therapy Efficacy in mCRC

City of Hope Medical Center

NCT07224841

RECRUITING Phase 1 387 participants

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

NCT06917079

RECRUITING Phase 1 188 participants

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Alterome Therapeutics

NCT06835569

RECRUITING Phase 1 170 participants

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

ALX Oncology

NCT07085091

RECRUITING NA 150 participants

Feasibility of a Multi-Channel Intervention to Promote Colorectal Cancer Screening Among American Indians in Oklahoma

University of Oklahoma

NCT07254910

RECRUITING Phase 2 136 participants

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

NGM Biopharmaceuticals

NCT07033026

RECRUITING Phase 1 130 participants

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

Sairopa B.V.

NCT05856981

RECRUITING Phase 1 128 participants

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Kumquat Biosciences

NCT06720987

ACTIVE NOT RECRUITING Phase 1 120 participants

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

Indaptus Therapeutics

NCT05651022

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 1
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the CRC, Colorectal Cancer Trial Landscape

11 indexed CRC, Colorectal Cancer studies · 10 recruiting (91%).

Phase mix: 1 late (III/IV) vs 7 early (I/II).

Top sponsor: City of Hope Medical Center (2 trials), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for CRC, Colorectal Cancer?

PlainTrial tracks 11 US clinical trials for CRC, Colorectal Cancer, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for CRC, Colorectal Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.