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NCT07085091 · ClinicalTrials.gov registry record · Phase 1

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

A Phase 1 study of Head and Neck Cancer and HNSCC, sponsored by ALX Oncology.

Recruiting
Registry status
Phase 1
Development phase
170
Enrollment target
7
Study locations

NCT07085091 is a Phase 1 study of Head and Neck Cancer and HNSCC that is actively recruiting participants, run by ALX Oncology. The registered enrollment target is 170 participants, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (35% lower). The trial reports 7 study locations across 7 states.

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The verdict

NCT07085091, a Phase 1 study of Head and Neck Cancer and HNSCC, is actively recruiting participants, sponsored by ALX Oncology.

RECRUITING
Registry status
Phase 1
Development phase
170 participants
Enrollment target
7
Study locations

Study Summary

A Phase 1, First in Human, Open-Label Multicenter Study to Evaluate ALX2004, an Antibody Drug Conjugate Targeting EGFR in Participants with Advanced or Metastatic Select Solid Tumors

Conditions Studied

Head and Neck Cancer HNSCC Colo-rectal Cancer CRC, Colorectal Cancer Esophageal Squamous Cell Carcinoma (ESCC) NSCLC (Advanced Non-small Cell Lung Cancer) ESCC

Interventions

  • DRUG ALX2004

Study Locations (7)

Florida

  • ALX Center 7 - Tampa

Michigan

  • ALX Center 3 - Grand Rapids

Oregon

  • ALX Center 6 - Portland

Texas

  • ALX Center 5 - Houston

Utah

  • ALX Center 4 - West Valley City

Virginia

  • ALX Center 2 - Fairfax

Washington

  • ALX Center 1 - Spokane

Trial Details

FieldValue
Enrollment Target 170 participants
Start Date 2025-08-18
Est. Completion 2027-12
Phase Phase 1

Sponsor

ALX Oncology

9 total trials

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What the Registry Record Tells You About NCT07085091

The ClinicalTrials.gov registry entry for NCT07085091 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 170 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (35% lower). The listed sponsor is ALX Oncology, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 1 intervention - of which ALX2004 is the first listed.

NCT07085091 reports 7 study locations spanning 7 distinct geographic areas - top geographies include Florida, Michigan, Oregon.

Frequently Asked Questions

What is clinical trial NCT07085091 about?

NCT07085091 is a clinical study titled "A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors". A Phase 1, First in Human, Open-Label Multicenter Study to Evaluate ALX2004, an Antibody Drug Conjugate Targeting EGFR in Participants with Advanced or Metastatic Select Solid Tumors

What is the current status of trial NCT07085091?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 170 participants. The study started on 2025-08-18. Estimated completion is 2027-12.

What conditions does trial NCT07085091 study?

This clinical trial studies the following conditions: Head and Neck Cancer, HNSCC, Colo-rectal Cancer, CRC, Colorectal Cancer, Esophageal Squamous Cell Carcinoma (ESCC).

What interventions are being tested in trial NCT07085091?

The interventions under investigation include: ALX2004 (DRUG).

Who is sponsoring clinical trial NCT07085091?

This trial is sponsored by ALX Oncology, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07085091 being conducted?

This trial has 7 study locations across Florida, Michigan, Oregon, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.