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Depression Disorders clinical trials
Every US clinical trial registered for Depression Disorders — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
11 US clinical trials · 10 currently recruiting
The research picture
Depression Disorders has 11 registered US clinical trials, 10 of them open to new participants right now — about 91% of the total.
- 10
- recruiting participants now
- 91%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: University of Texas Southwestern Medical Center
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients
Dartmouth-Hitchcock Medical Center
NCT06898593
Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study
Aura
NCT06664944
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
NCT06793397
Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression
Massachusetts General Hospital
NCT07082998
Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity
Deliberate Solutions
NCT06923995
AI Platform for Fatigue and Depression Detection
Brijesh Patel
NCT07218263
Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
Gaize
NCT07389473
Teen Recovery Through Inspiration, Support, and Empowerment
University of Texas Southwestern Medical Center
NCT07170657
Recovery Through Inspiration, Support, and Empowerment
University of Texas Southwestern Medical Center
NCT07051200
Meditative Neurofeedback for Depression
University of California, San Diego
NCT06675240
Effectiveness of the Adapt for Life, Mental Wellness and Suicide Prevention Program
Children's Hospital Medical Center, Cincinnati
NCT06979479
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Depression Disorders Trial Landscape
ClinicalTrials.gov lists 11 US studies indexed under Depression Disorders, and 10 of those are currently open to recruitment — roughly 91% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Depression Disorders shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Depression Disorders is led by University of Texas Southwestern Medical Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Depression Disorders?
PlainTrial tracks 11 US clinical trials for Depression Disorders, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Depression Disorders?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.