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ACTIVE NOT RECRUITING Phase 1

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

NCT05651022 · View on ClinicalTrials.gov ↗

Study Summary

INDP-D101 is a Phase 1/2, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of Decoy20 as monotherapy and in combination with tislelizumab in patients with locally advanced or metastatic solid tumors.

Interventions

  • DRUG Tislelizumab
  • DRUG Decoy20

Study Locations (12)

Ohio

  • Gabrail Cancer & Research Center — Canton
  • UH Seidman Cancer Center — Cleveland
  • Cleveland Clinic Taussig Cancer Center — Cleveland

California

  • University of Southern California- Norris Cancer Center — Los Angeles
  • Hoag Memorial Hospital Presbyterian — Newport Beach

Georgia

  • Winship Cancer Institute of Emory University — Atlanta

Michigan

  • The Barbara Ann Karmanos Cancer Institute — Detroit

Missouri

  • Washington University, Siteman Cancer Center — St Louis

New Jersey

  • Atlantic Health System — Morristown

New York

  • Roswell Park Comprehensive Cancer Center — Buffalo

Pennsylvania

  • Fox Chase Cancer Center — Philadelphia

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2023-02-28
Est. Completion 2027-09-30
Phase Phase 1

Sponsor

Indaptus Therapeutics

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05651022

The ClinicalTrials.gov registry entry for NCT05651022 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indaptus Therapeutics, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 8 conditions, with Solid Tumor, Adult appearing as the primary indexed condition, and to 2 interventions — of which Tislelizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05651022 reports 12 study locations spanning 9 distinct geographic areas — top geographies include Ohio, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05651022 about?

NCT05651022 is a clinical study titled "Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors". INDP-D101 is a Phase 1/2, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of Decoy20 as monotherapy and in combination with tislelizumab in patients with locally advanced or metastatic solid tumors.

What is the current status of trial NCT05651022?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 120 participants. The study started on 2023-02-28. Estimated completion is 2027-09-30.

What conditions does trial NCT05651022 study?

This clinical trial studies the following conditions: Solid Tumor, Adult, Pancreatic Adenocarcinoma, CRC (Colorectal Cancer), MSI-H Cancer, UC (Urothelial Cancer). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05651022?

The interventions under investigation include: Tislelizumab (DRUG), Decoy20 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05651022?

This trial is sponsored by Indaptus Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05651022 being conducted?

This trial has 12 study locations across California, Georgia, Michigan, Missouri, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial