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ClinicalTrials.gov 4 recruiting now official registry

Cough clinical trials

Every US clinical trial registered for Cough — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

13 US clinical trials · 4 currently recruiting

The research picture

Cough has 13 registered US clinical trials, 4 of them open to new participants right now — about 31% of the total.

4
recruiting participants now
31%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
3
top sponsor: Bellus Health Inc. - a GSK company

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 3 975 participants

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Bellus Health Inc. - a GSK company

NCT05600777

RECRUITING Phase 4 160 participants

The Mechanism Versus PPI Trial

University of California, San Diego

NCT06999577

RECRUITING NA 60 participants

Stimulation of the Larynx to Treat Unexplained Chronic Cough

University of Minnesota

NCT05273190

RECRUITING 50 participants

Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough

University of Alabama at Birmingham

NCT04642352

ACTIVE NOT RECRUITING Phase 3 825 participants

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Bellus Health Inc. - a GSK company

NCT05599191

ACTIVE NOT RECRUITING 39 participants

Work of Breathing Assessment in Triage Scale

CHRISTUS Health

NCT05479929

COMPLETED Phase 4 244 participants

A Clinical Evidence Study Evaluating Quality of Life Parameters Following Treatment With Robitussin

HALEON

NCT06716645

COMPLETED NA 120 participants

Effect of Agave Syrup, Placebo, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Infants/Toddlers and Their Parents

Penn State University

NCT01721395

COMPLETED Phase 1 105 participants

Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep

Penn State University

NCT00127686

COMPLETED Phase 1 32 participants

A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years of Age

Bellus Health Inc. - a GSK company

NCT06222892

COMPLETED Phase 1 22 participants

Cough Desensitization Therapy: Pilot 2

University of Montana

NCT05226299

COMPLETED Early Phase 1 19 participants

Cough Desensitization Therapy for Cough Hypersensitivity Syndrome

University of Montana

NCT04256733

COMPLETED NA 12 participants

Stimulation With Wire Leads to Restore Cough

MetroHealth Medical Center

NCT01659541

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 3 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cough Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Cough, and 4 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Cough shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Cough is led by Bellus Health Inc. - a GSK company with 3 indexed trials, alongside 8 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cough?

PlainTrial tracks 13 US clinical trials for Cough, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cough?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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