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A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
NCT05600777 · View on ClinicalTrials.gov ↗
Study Summary
This is a randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of BLU-5937 in participants with Refractory Chronic Cough (RCC).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG BLU-5937
Study Locations (20)
Florida
- GSK Investigational Site — Daytona Beach
- GSK Investigational Site — Fort Lauderdale
- GSK Investigational Site — Jacksonville
- GSK Investigational Site — Leesburg
- GSK Investigational Site — Santa Rosa Beach
- GSK Investigational Site — Sarasota
- GSK Investigational Site — Sweetwater
California
- GSK Investigational Site — Los Angeles
- GSK Investigational Site — Los Angeles
- GSK Investigational Site — Paramount
- GSK Investigational Site — San Diego
- GSK Investigational Site — San Diego
- GSK Investigational Site — San Jose
Colorado
- GSK Investigational Site — Aurora
- GSK Investigational Site — Colorado Springs
- GSK Investigational Site — Wheat Ridge
Alabama
- GSK Investigational Site — Foley
Arizona
- GSK Investigational Site — Phoenix
District of Columbia
- GSK Investigational Site — Washington D.C.
Georgia
- GSK Investigational Site — Cumming
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 975 participants |
| Start Date | 2022-12-05 |
| Est. Completion | 2027-03-23 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05600777
The ClinicalTrials.gov registry entry for NCT05600777 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 975 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bellus Health Inc. - a GSK company, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Cough appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05600777 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Florida, California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05600777 about?
NCT05600777 is a clinical study titled "A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough". This is a randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of BLU-5937 in participants with Refractory Chronic Cough (RCC).
What is the current status of trial NCT05600777?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 975 participants. The study started on 2022-12-05. Estimated completion is 2027-03-23.
What conditions does trial NCT05600777 study?
This clinical trial studies the following conditions: Cough, Refractory Chronic Cough. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05600777?
The interventions under investigation include: Placebo (DRUG), BLU-5937 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05600777?
This trial is sponsored by Bellus Health Inc. - a GSK company, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05600777 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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