Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00127686 · ClinicalTrials.gov registry record · Phase 1
Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep
A Phase 1 study of Respiratory Tract Infections and Cough, sponsored by Penn State University.
- Completed
- Registry status
- Phase 1
- Development phase
- 105
- Enrollment target
- 1
- Study location
NCT00127686 is a Phase 1 study of Respiratory Tract Infections and Cough that has completed, run by Penn State University. The registered enrollment target is 105 participants, below the 2,767-participant average among 15 other Respiratory Tract Infections trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00127686, a Phase 1 study of Respiratory Tract Infections and Cough, has completed, sponsored by Penn State University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 105 participants
- Enrollment target
- 1
- Study location
Study Summary
Cough is the most common reason for an acute care doctor's visit in the United States. Cough can affect sleep for both coughing children and their parents. The American Academy of Pediatrics does not endorse the use of dextromethorphan (DM), the most common over-the-counter (OTC) cough medication because of a lack of efficacy data and some potential for toxicity, particularly when taken in excess. In fact, DM has previously been shown to be no better than a placebo for cough in children. Therefore, alternative, therapeutic agents are needed. Honey anecdotally provides relief for symptoms due to upper respiratory tract infection (URI). This study seeks to use a survey to evaluate whether a single dose of honey and/or DM is better than no treatment at all for controlling nocturnal cough in children with URI and the effect of the treatments on sleep quality for coughing children and their parents. A single dose of honey or DM will be superior to no treatment for control of nocturnal cough due to upper URI as rated by both parents and children and will improve the sleep quality for those children and parents. Compared to DM, honey will be superior for controlling nocturnal cough due to upper URI (also based on child and parental report).
Conditions Studied
Interventions
- DRUG Dextromethorphan
- DRUG Buckwheat Honey
Study Locations (1)
Pennsylvania
- Penn State Milton S. Hershey Medical Center - Hershey
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2005-09 |
| Est. Completion | 2006-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00127686
The ClinicalTrials.gov registry entry for NCT00127686 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,767-participant average among 15 other Respiratory Tract Infections trials with a reported enrollment target (96% lower). The listed sponsor is Penn State University, which has 219 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Respiratory Tract Infections appearing as the primary indexed condition, and to 2 interventions - of which Dextromethorphan is the first listed.
NCT00127686 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00127686 about?
NCT00127686 is a clinical study titled "Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep". Cough is the most common reason for an acute care doctor's visit in the United States. Cough can affect sleep for both coughing children and their parents. The American Academy of Pediatrics does not endorse the use of dextromethorphan (DM), the most common over-the-counter (OTC) cough medication be...
What is the current status of trial NCT00127686?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2005-09. Estimated completion is 2006-12.
What conditions does trial NCT00127686 study?
This clinical trial studies the following conditions: Respiratory Tract Infections, Cough.
What interventions are being tested in trial NCT00127686?
The interventions under investigation include: Dextromethorphan (DRUG), Buckwheat Honey (DRUG).
Who is sponsoring clinical trial NCT00127686?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00127686 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Tract Infections
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Study to Evaluate the Safety, Tolerability and Immunogenicity of an Investigational RSV Vaccine Candidate (Ad26.RSV.preF) in Adults 18 to 50 Years of Age, and RSV-seropositive Toddlers 12 to 24 Months of Age
COMPLETED · Phase 1
-
Comparison of Nasopharyngeal Swab v. Nasopharyngeal Saline Wash or Saliva Collection in Testing for Respiratory Viruses
RECRUITING · NA
-
How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.
RECRUITING · NA
-
An Adjunct Test Distinguishing Bacterial From Viral Etiology Improves Resource Utilization and Efficiency in the ED.
RECRUITING · NA
-
Beetroot Juice NO Cold Study
RECRUITING · Phase 2
-
Dose Finding Study to Determine if BEZ235 Alone or in Combination With RAD001 Decreases the Incidence of Respiratory Tract Infections in the Elderly
ACTIVE NOT RECRUITING · Phase 2
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.