Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04642352 · ClinicalTrials.gov registry record
Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough
A clinical trial of Cough, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT04642352: Recruiting study of Cough, sponsored by University of Alabama at Birmingham.
NCT04642352 is a study of Cough that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 50 participants, below the 218-participant average among 12 other Cough trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04642352, a study of Cough, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate if office-based injection of a local anesthetic/steroid combination at the area of one superior laryngeal nerve can decrease cough frequency and alleviate symptoms of chronic cough in patients with neurogenic cough.
Primary Outcome
The Leicester Cough Questionnaire consists of 19 questions designed to assess the impact of cough on various aspects of a participant's quality of life. Scores are chosen from a Likert scale from 1 to 7, with 1 representing "all of the time" and 7 representing "none of the time." Scores would decrease if symptoms improved.
Conditions Studied
Interventions
- DRUG superior laryngeal nerve block
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-01-03 |
| Est. Completion | 2026-10 |
What NCT04642352 shows while recruiting
NCT04642352 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 218-participant average among 12 other Cough trials with a reported enrollment target (77% lower).
The record links to 1 condition, with Cough appearing as the primary indexed condition, and to 1 intervention - of which superior laryngeal nerve block is the first listed.
NCT04642352 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT04642352 about?
NCT04642352 is a clinical study titled "Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough". The purpose of this study is to evaluate if office-based injection of a local anesthetic/steroid combination at the area of one superior laryngeal nerve can decrease cough frequency and alleviate symptoms of chronic cough in patients with neurogenic cough.
What is the current status of trial NCT04642352?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2022-01-03. Estimated completion is 2026-10.
What conditions does trial NCT04642352 study?
This clinical trial studies the following conditions: Cough.
What interventions are being tested in trial NCT04642352?
The interventions under investigation include: superior laryngeal nerve block (DRUG).
Who is sponsoring clinical trial NCT04642352?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04642352 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cough
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04642352's enrollment target sits among peer trials
50 8th of 12 higher than 5 of 12 other Cough trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cough trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
RECRUITING · Phase 3
-
The Mechanism Versus PPI Trial
RECRUITING · Phase 4
-
Stimulation of the Larynx to Treat Unexplained Chronic Cough
RECRUITING · NA
-
Work of Breathing Assessment in Triage Scale
ACTIVE NOT RECRUITING
-
A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
ACTIVE NOT RECRUITING · Phase 3
-
Stimulation With Wire Leads to Restore Cough
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI