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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Congenital Adrenal Hyperplasia: early-phase trial registry

4 of 9 indexed Congenital Adrenal Hyperplasia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 4 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Congenital Adrenal Hyperplasia: 9 US clinical trials tracked, 4 recruiting.

Congenital Adrenal Hyperplasia is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Crinetics Pharmaceuticals, running 3 of these trials.

Enrollment posture brief

Registry condition congenital-adrenal-hyperplasia

OPEN 4 | RECR 44% | LATE 3 | EARLY 6 | RANK #1916 | SPON 3

Nearest open-share peer: Acute Ischemic Stroke (44% recruiting · 27 trials)

Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Congenital Adrenal Hyper (th…44%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia lists 4 open slots (44% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Congenital Adrenal Hyperplasia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Congenital Adrenal Hyperplasia is recruiting below its size-band peers.

    4 of 9 indexed trials (44.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Congenital Adrenal Hyperplasia research.

    Crinetics Pharmaceuticals accounts for 3 of 9 trials (33.3%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Congenital Adrenal Hyperplasia enrolment sits around 103 participants.

    Median target enrolment is 103 among the 9 trials that report a genuine target (sentinel values excluded). 4 of those (44.4%) plan for fewer than 100 participants.

  4. Congenital Adrenal Hyperplasia research is mostly interventional.

    9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 23Phase 33

Open and recent trials

9 total, page 1 of 1

RECRUITING Phase 2 153 participants

A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

Crinetics Pharmaceuticals

NCT07159841

RECRUITING Phase 3 150 participants

A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia

Crinetics Pharmaceuticals

NCT07144163

RECRUITING Phase 2 150 participants

An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

Crinetics Pharmaceuticals

NCT06712823

RECRUITING Phase 1 42 participants

A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia

H. Lundbeck A/S

NCT05669950

ACTIVE NOT RECRUITING Phase 3 182 participants

Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia

Neurocrine Biosciences

NCT04490915

ACTIVE NOT RECRUITING Phase 3 103 participants

Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Participants With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study)

Neurocrine Biosciences

NCT04806451

ACTIVE NOT RECRUITING Phase 1 8 participants

A Study of Gene Therapy for Classic Congenital Adrenal Hyperplasia (CAH)

Adrenas Therapeutics

NCT04783181

COMPLETED Phase 1 20 participants

Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia

Neurocrine UK Limited

NCT00519818

COMPLETED Phase 2 11 participants

Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

Spruce Biosciences

NCT03687242

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 3

Named interventions

Most-linked intervention names on Congenital Adrenal Hyperplasia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
4 trials
Crinecerfont Drug
2 trials
Atumelnant Drug
2 trials
SPR001 Drug
1 trials
Cortef Drug
1 trials
Chronocort Drug
1 trials
AAV BBP-631 Biological
1 trials
atumelnant (CRN04894) Drug
1 trials

US sites by state

Facility locations filed on Congenital Adrenal Hyperplasia trials. A trial with sites in several states counts in each.

Minnesota 6 trials
Michigan 6 trials
Pennsylvania 4 trials
North Carolina 3 trials
Maryland 3 trials
Indiana 3 trials
Georgia 3 trials
California 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Congenital Adrenal Hyperplasia page

9 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Congenital Adrenal Hyperplasia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Crinetics Pharmaceuticals sponsors the most Congenital Adrenal Hyperplasia trials on record, review their full trial history before evaluating a specific study. See Crinetics Pharmaceuticals's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Congenital Adrenal Hyperplasia condition card totals 9 registered trials; most-linked intervention Placebo; top US site state Minnesota. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.