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NCT07144163 · ClinicalTrials.gov registry record · Phase 3
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
A Phase 3 study of Congenital Adrenal Hyperplasia and Classic Congenital Adrenal Hyperplasia, sponsored by Crinetics Pharmaceuticals.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 150
- Enrollment target
- 8
- Study locations
NCT07144163: Recruiting Phase 3 study of Congenital Adrenal Hyperplasia and Classic Congenital Adrenal Hyperplasia, sponsored by Crinetics Pharmaceuticals.
NCT07144163 is a Phase 3 study of Congenital Adrenal Hyperplasia and Classic Congenital Adrenal Hyperplasia that is actively recruiting participants, run by Crinetics Pharmaceuticals. The registered enrollment target is 150 participants, above the 84-participant average among 8 other Congenital Adrenal Hyperplasia trials with a reported enrollment target (79% higher). The trial reports 8 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07144163, a Phase 3 study of Congenital Adrenal Hyperplasia and Classic Congenital Adrenal Hyperplasia, is actively recruiting participants, sponsored by Crinetics Pharmaceuticals.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 150 participants
- Enrollment target
- 8
- Study locations
Study Summary
The purpose of this study is to evaluate the efficacy, safety, PK, and PD of atumelnant in adults with classic CAH due to 21-OHD.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Atumelnant
Study Locations (8)
Queensland
- Crinetics Study Site - Herston
- Crinetics Study Site - Woolloongabba
Michigan
- Crinetics Study Site - Ann Arbor
Buenos Aires F.D.
- Crinetics Study Site - Buenos Aires
South Australia
- Crinetics Study Site - Adelaide
Victoria
- Crinetics Study Site - Parkville
Western Australia
- Crinetics Study Site - Nedlands
São Paulo
- Crinetics Study Site - São Paulo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2025-12-11 |
| Est. Completion | 2027-05 |
| Phase | Phase 3 |
What NCT07144163 shows while recruiting
NCT07144163 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 84-participant average among 8 other Congenital Adrenal Hyperplasia trials with a reported enrollment target (79% higher).
The record links to 2 conditions, with Congenital Adrenal Hyperplasia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07144163 lists 8 locations in 7 states (Queensland, Michigan, Buenos Aires F.D.).
Frequently Asked Questions
What is clinical trial NCT07144163 about?
NCT07144163 is a clinical study titled "A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia". The purpose of this study is to evaluate the efficacy, safety, PK, and PD of atumelnant in adults with classic CAH due to 21-OHD.
What is the current status of trial NCT07144163?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2025-12-11. Estimated completion is 2027-05.
What conditions does trial NCT07144163 study?
This clinical trial studies the following conditions: Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia.
What interventions are being tested in trial NCT07144163?
The interventions under investigation include: Placebo (DRUG), Atumelnant (DRUG).
Who is sponsoring clinical trial NCT07144163?
This trial is sponsored by Crinetics Pharmaceuticals, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07144163 being conducted?
This trial has 8 study locations across Michigan, Buenos Aires F.D., Queensland, South Australia, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Congenital Adrenal Hyperplasia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07144163's enrollment target sits among peer trials
150 3rd of 8 higher than 5 of 8 other Congenital Adrenal Hyperplasia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Congenital Adrenal Hyperplasia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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