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A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
NCT07144163 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the efficacy, safety, PK, and PD of atumelnant in adults with classic CAH due to 21-OHD.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Atumelnant
Study Locations (8)
Queensland
- Crinetics Study Site — Herston
- Crinetics Study Site — Woolloongabba
Michigan
- Crinetics Study Site — Ann Arbor
Buenos Aires F.D.
- Crinetics Study Site — Buenos Aires
South Australia
- Crinetics Study Site — Adelaide
Victoria
- Crinetics Study Site — Parkville
Western Australia
- Crinetics Study Site — Nedlands
São Paulo
- Crinetics Study Site — São Paulo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2025-12-11 |
| Est. Completion | 2027-05 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07144163
The ClinicalTrials.gov registry entry for NCT07144163 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Crinetics Pharmaceuticals, which has 9 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Congenital Adrenal Hyperplasia appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07144163 reports 8 study locations spanning 7 distinct geographic areas — top geographies include Queensland, Michigan, Buenos Aires F.D.. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07144163 about?
NCT07144163 is a clinical study titled "A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia". The purpose of this study is to evaluate the efficacy, safety, PK, and PD of atumelnant in adults with classic CAH due to 21-OHD.
What is the current status of trial NCT07144163?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2025-12-11. Estimated completion is 2027-05.
What conditions does trial NCT07144163 study?
This clinical trial studies the following conditions: Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07144163?
The interventions under investigation include: Placebo (DRUG), Atumelnant (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07144163?
This trial is sponsored by Crinetics Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07144163 being conducted?
This trial has 8 study locations across Michigan, Buenos Aires F.D., Queensland, South Australia, Victoria. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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