Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Common Variable Immunodeficiency: early-phase trial registry
5 of 8 indexed Common Variable Immunodeficiency trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 5 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Common Variable Immunodeficiency: 8 US clinical trials tracked, 5 recruiting.
Common Variable Immunodeficiency is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.
Enrollment posture brief
Registry condition common-variable-immunodeficiency
OPEN 5 | RECR 63% | LATE 1 | EARLY 4 | RANK #2176 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Adolescent (63% recruiting · 16 trials)
Common Variable Immunodeficiency lists 5 open slots (63% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Common Variable Immunodeficiency on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Common Variable Immunodeficiency is recruiting above its size-band peers.
5 of 8 indexed trials (62.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Common Variable Immunodeficiency research.
National Cancer Institute (NCI) accounts for 3 of 8 trials (37.5%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Common Variable Immunodeficiency trials plan to enrol fewer than 100 people.
Median target enrolment is 71 among the 8 trials that report a genuine target (sentinel values excluded). 5 of those (62.5%) plan for fewer than 100 participants.
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Common Variable Immunodeficiency research is mostly interventional.
6 interventional and 2 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Natural History of Bronchiectasis
National Heart, Lung, and Blood Institute (NHLBI)
NCT00943514
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
National Cancer Institute (NCI)
NCT02579967
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity
National Cancer Institute (NCI)
NCT04339777
Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease
Children's Hospital Medical Center, Cincinnati
NCT04925375
Usage of Spirometry in Managing IgG Therapy in CVID with Airway Disease
University of Alabama at Birmingham
NCT05193552
COVID-19 Vaccine Responses in PIDD Subjects
Duke University
NCT05321407
Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
National Cancer Institute (NCI)
NCT03663933
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Masonic Cancer Center, University of Minnesota
NCT01652092
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 4 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Common Variable Immunodeficiency records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Common Variable Immunodeficiency trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Common Variable Immunodeficiency page
8 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Common Variable Immunodeficiency trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Cancer Institute (NCI) sponsors the most Common Variable Immunodeficiency trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Common Variable Immunodeficiency condition card totals 8 registered trials; most-linked intervention GVHD Prophylaxis; top US site state Minnesota. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.