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NCT00943514 · ClinicalTrials.gov registry record
Natural History of Bronchiectasis
A clinical trial of Cystic Fibrosis and Bronchiectasis, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Recruiting
- Registry status
- 900
- Enrollment target
- 1
- Study location
NCT00943514: Recruiting study of Cystic Fibrosis and Bronchiectasis, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00943514 is a study of Cystic Fibrosis and Bronchiectasis that is actively recruiting participants, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 900 participants, above the 174-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (417% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00943514, a study of Cystic Fibrosis and Bronchiectasis, is actively recruiting participants, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- RECRUITING
- Registry status
- 900 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: * Bronchiectasis is a disease characterized by airways that are inflamed, abnormally dilated, and chronically infected. Individuals with bronchiectasis have a history of chronic and recurring respiratory infections. Depending on the underlying cause, these infections may involve the entire respiratory tract, resulting in sinus, ear, and lung disease. * Bronchiectasis continues to be a significant problem in developing countries and in specific groups of individuals, particularly in people who have cystic fibrosis. Although treatments are available or under development for bronchiectasis related to cystic fibrosis, many of the disease-specific treatments may not be effective for bronchiectasis not related to cystic fibrosis. Objectives: \- To study the natural history of bronchiectasis to identify inherited and immune factors that may explain why certain individuals have chronic recurring infections. Eligibility: * Individuals 5 years of age and older who have an established diagnosis of bronchiectasis or a history of chronic/recurring respiratory infections. * Direct family members (e.g., parents, siblings, children) of patients in the study may also be asked to participate. Design: * Potential participants will be screened with an initial clinic evaluation and full medical history, as well as a general quality of life and respiratory symptom questionnaire. * The following standard procedures may be done as part of the study: air sampling from the nose; imaging studies, which may include an x-ray or computed tomography (CT), lung function tests; and collection of samples of blood, urine, and sputum (phlegm or mucus). Other tests may be performed as required by the researchers, and will be explained to patients as needed. * Both patients and relatives (if asked to participate) will provide the following samples: blood or buccal (cheek swab) cells for genetic testing, sputum, and urine. * To prevent infections and potential disease progression, pati
Primary Outcome
Identify causes and/or underlying conditions associated with bronchiectasis.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 900 participants |
| Start Date | 2009-08-01 |
What NCT00943514 shows while recruiting
NCT00943514 is an observational study that tracks outcomes without assigning an intervention. The registered 900 participants enrollment target is mid-sized for trials with a published cap, above the 174-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (417% higher).
The record links to 4 conditions, with Cystic Fibrosis appearing as the primary indexed condition, and to 0 interventions.
NCT00943514 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00943514 about?
NCT00943514 is a clinical study titled "Natural History of Bronchiectasis". Background: * Bronchiectasis is a disease characterized by airways that are inflamed, abnormally dilated, and chronically infected. Individuals with bronchiectasis have a history of chronic and recurring respiratory infections. Depending on the underlying cause, these infections may involve the ent...
What is the current status of trial NCT00943514?
This trial is currently recruiting. The enrollment target is 900 participants. The study started on 2009-08-01.
What conditions does trial NCT00943514 study?
This clinical trial studies the following conditions: Cystic Fibrosis, Bronchiectasis, Autoimmune Disease, Common Variable Immunodeficiency.
Who is sponsoring clinical trial NCT00943514?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00943514 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cystic Fibrosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00943514's enrollment target sits among peer trials
900 4th of 169 higher than 166 of 169 other Cystic Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cystic Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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