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ClinicalTrials.gov 10 recruiting now official registry

Colorectal Cancer Metastatic clinical trials

Every US clinical trial registered for Colorectal Cancer Metastatic — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

19 US clinical trials · 10 currently recruiting

The research picture

Colorectal Cancer Metastatic has 19 registered US clinical trials, 10 of them open to new participants right now — about 53% of the total.

10
recruiting participants now
53%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Northwell Health

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 2,700 participants

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

Mainz Biomed

NCT06864338

RECRUITING 80 participants

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Northwestern University

NCT06698146

RECRUITING Phase 2 80 participants

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

Michael J Cavnar, MD

NCT07201519

RECRUITING Phase 2 64 participants

Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer

HealthPartners Institute

NCT06605430

RECRUITING Phase 1 53 participants

A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

University of Chicago

NCT05200442

RECRUITING 25 participants

Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases

University of Rochester

NCT05248581

RECRUITING Phase 2 24 participants

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Weill Medical College of Cornell University

NCT06300463

RECRUITING Phase 2 20 participants

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

Buzzard Pharmaceuticals

NCT06634875

RECRUITING Early Phase 1 10 participants

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis

Northwell Health

NCT07193862

RECRUITING Early Phase 1 10 participants

INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases

Northwell Health

NCT07172282

ACTIVE NOT RECRUITING 169 participants

Assessing How Normal Variations in CT Scanning Affects Its Interpretation

Memorial Sloan Kettering Cancer Center

NCT03038568

ACTIVE NOT RECRUITING Phase 1 75 participants

Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer

University of Southern California

NCT03657641

ACTIVE NOT RECRUITING 55 participants

Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis

University of Chicago

NCT04157322

ACTIVE NOT RECRUITING Phase 1 30 participants

A Phase 1b Study of WU-NK-101 in Combination With Cetuximab

Wugen

NCT05674526

ACTIVE NOT RECRUITING Phase 2 18 participants

Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.

Treos Bio Limited

NCT05243862

COMPLETED Phase 2 181 participants

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01298570

COMPLETED Phase 2 58 participants

Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer

The Rogosin Institute

NCT01053013

COMPLETED Phase 2 36 participants

A Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal Cancer

Massachusetts General Hospital

NCT03144804

COMPLETED NA 4 participants

TheraSphere® For Treatment of Metastases in Liver

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04517643

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Colorectal Cancer Metastatic Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under Colorectal Cancer Metastatic, and 10 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Colorectal Cancer Metastatic shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Colorectal Cancer Metastatic is led by Northwell Health with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Colorectal Cancer Metastatic?

PlainTrial tracks 19 US clinical trials for Colorectal Cancer Metastatic, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Colorectal Cancer Metastatic?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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