Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Colorectal Cancer Metastatic clinical trials
Every US clinical trial registered for Colorectal Cancer Metastatic — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
19 US clinical trials · 10 currently recruiting
The research picture
Colorectal Cancer Metastatic has 19 registered US clinical trials, 10 of them open to new participants right now — about 53% of the total.
- 10
- recruiting participants now
- 53%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Northwell Health
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test
Mainz Biomed
NCT06864338
Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
Northwestern University
NCT06698146
Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy
Michael J Cavnar, MD
NCT07201519
Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer
HealthPartners Institute
NCT06605430
A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer
University of Chicago
NCT05200442
Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
University of Rochester
NCT05248581
Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
Weill Medical College of Cornell University
NCT06300463
Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)
Buzzard Pharmaceuticals
NCT06634875
Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis
Northwell Health
NCT07193862
INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases
Northwell Health
NCT07172282
Assessing How Normal Variations in CT Scanning Affects Its Interpretation
Memorial Sloan Kettering Cancer Center
NCT03038568
Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer
University of Southern California
NCT03657641
Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis
University of Chicago
NCT04157322
A Phase 1b Study of WU-NK-101 in Combination With Cetuximab
Wugen
NCT05674526
Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.
Treos Bio Limited
NCT05243862
Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer
UNC Lineberger Comprehensive Cancer Center
NCT01298570
Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer
The Rogosin Institute
NCT01053013
A Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal Cancer
Massachusetts General Hospital
NCT03144804
TheraSphere® For Treatment of Metastases in Liver
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04517643
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Colorectal Cancer Metastatic Trial Landscape
ClinicalTrials.gov lists 19 US studies indexed under Colorectal Cancer Metastatic, and 10 of those are currently open to recruitment — roughly 53% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Colorectal Cancer Metastatic shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Colorectal Cancer Metastatic is led by Northwell Health with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Colorectal Cancer Metastatic?
PlainTrial tracks 19 US clinical trials for Colorectal Cancer Metastatic, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Colorectal Cancer Metastatic?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.