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ClinicalTrials.gov 10 recruiting now early-phase tilt small index

Colorectal Cancer Metastatic: early-phase trial registry

10 of 19 indexed Colorectal Cancer Metastatic trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 10 currently recruiting · #902 of 28,707 conditions by registered trial count

Colorectal Cancer Metastatic: 19 US clinical trials tracked, 10 recruiting.

Colorectal Cancer Metastatic is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Northwell Health, running 2 of these trials.

Enrollment posture brief

Registry condition colorectal-cancer-metastatic

OPEN 10 | RECR 53% | LATE 0 | EARLY 13 | RANK #902 | SPON 2

Nearest open-share peer: Knee Pain Chronic (53% recruiting · 19 trials)

Colorectal Cancer Metast (th…53%Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Colorectal Cancer Metastatic

Colorectal Cancer Metastatic lists 10 open slots (53% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Colorectal Cancer Metastatic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Colorectal Cancer Metastatic is recruiting above its size-band peers.

    10 of 19 indexed trials (52.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Colorectal Cancer Metastatic trials is spread across many organizations.

    Northwell Health accounts for 2 of 19 trials (10.5%). 17 distinct sponsors appear on at least one study for this condition label.

  3. Most Colorectal Cancer Metastatic trials plan to enrol fewer than 100 people.

    Median target enrolment is 53 among the 19 trials that report a genuine target (sentinel values excluded). 16 of those (84.2%) plan for fewer than 100 participants.

  4. Colorectal Cancer Metastatic research is mostly interventional.

    14 interventional and 5 observational studies make up this index (73.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 28

Open and recent trials

19 total, page 1 of 1

RECRUITING 2,700 participants

Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test

Mainz Biomed

NCT06864338

RECRUITING 80 participants

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Northwestern University

NCT06698146

RECRUITING Phase 2 80 participants

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

Michael J Cavnar, MD

NCT07201519

RECRUITING Phase 2 64 participants

Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer

HealthPartners Institute

NCT06605430

RECRUITING Phase 1 53 participants

A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

University of Chicago

NCT05200442

RECRUITING 25 participants

Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases

University of Rochester

NCT05248581

RECRUITING Phase 2 24 participants

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Weill Medical College of Cornell University

NCT06300463

RECRUITING Phase 2 20 participants

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

Buzzard Pharmaceuticals

NCT06634875

RECRUITING Early Phase 1 10 participants

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis

Northwell Health

NCT07193862

RECRUITING Early Phase 1 10 participants

INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases

Northwell Health

NCT07172282

ACTIVE NOT RECRUITING 169 participants

Assessing How Normal Variations in CT Scanning Affects Its Interpretation

Memorial Sloan Kettering Cancer Center

NCT03038568

ACTIVE NOT RECRUITING Phase 1 75 participants

Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer

University of Southern California

NCT03657641

ACTIVE NOT RECRUITING 55 participants

Plasma 5hmC Signatures as a Marker of Colorectal / Appendiceal Peritoneal Metastasis

University of Chicago

NCT04157322

ACTIVE NOT RECRUITING Phase 1 30 participants

A Phase 1b Study of WU-NK-101 in Combination With Cetuximab

Wugen

NCT05674526

ACTIVE NOT RECRUITING Phase 2 18 participants

Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.

Treos Bio Limited

NCT05243862

COMPLETED Phase 2 181 participants

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01298570

COMPLETED Phase 2 58 participants

Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer

The Rogosin Institute

NCT01053013

COMPLETED Phase 2 36 participants

A Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal Cancer

Massachusetts General Hospital

NCT03144804

COMPLETED NA 4 participants

TheraSphere® For Treatment of Metastases in Liver

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04517643

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 8

Named interventions

Most-linked intervention names on Colorectal Cancer Metastatic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

RENCA macrobeads Biological
1 trials
Therasphere Therapy Other
1 trials
prospective single arm biomarker (plasma cell-free DNA hydroxymethylation) study Diagnostic test
1 trials
Cetuximab - Cohort Expansion Biological
1 trials
WU-NK-101 - Cohort Expansion Biological
1 trials
Cetuximab - Dose Escalation Drug
1 trials
WU-NK-101 - Dose Escalation Biological
1 trials
PolyPEPI1018 Drug
1 trials

US sites by state

Facility locations filed on Colorectal Cancer Metastatic trials. A trial with sites in several states counts in each.

New York 8 trials
Illinois 3 trials
Florida 3 trials
California 3 trials
North Carolina 2 trials
Minnesota 2 trials
Kentucky 2 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Colorectal Cancer Metastatic page

19 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 10 Colorectal Cancer Metastatic trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Northwell Health sponsors the most Colorectal Cancer Metastatic trials on record, review their full trial history before evaluating a specific study. See Northwell Health's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Colorectal Cancer Metastatic condition card totals 19 registered trials; most-linked intervention RENCA macrobeads; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.