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Cigarette Smoking-Related Carcinoma clinical trials
12 of 22 indexed Cigarette Smoking-Related Carcinoma trials are currently recruiting.
22 US clinical trials · 12 currently recruiting
Cigarette Smoking-Related Carcinoma is the subject of 22 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Ohio State University Comprehensive Cancer Center, running 6 of these trials.
The research picture
Cigarette Smoking-Related Carcinoma has 22 registered US clinical trials, 12 of them open to new participants right now, about 55% of the total.
- 12
- recruiting participants now
- 55%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 6
- top sponsor: Ohio State University Comprehensive Cancer Center
Active & Recent Trials
22 total, page 1 of 1
Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial
M.D. Anderson Cancer Center
NCT04604509
A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
Ohio State University Comprehensive Cancer Center
NCT06260683
Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia
Ohio State University Comprehensive Cancer Center
NCT06763536
A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trial
Fred Hutchinson Cancer Center
NCT06145763
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program
Alliance for Clinical Trials in Oncology
NCT05008848
Smoking Cessation Intervention Development for Homeless Youth
Ohio State University Comprehensive Cancer Center
NCT06754215
Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)
Roswell Park Cancer Institute
NCT07167225
CONNECTing to LungCare
University of California, San Francisco
NCT06213532
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers
National Cancer Institute (NCI)
NCT05121051
Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance
Roswell Park Cancer Institute
NCT07439471
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
Roswell Park Cancer Institute
NCT06816459
Studying Flavors and Cooling Agents in Oral Nicotine Pouches to Understand User Preferences
Ohio State University Comprehensive Cancer Center
NCT07111234
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
Fred Hutchinson Cancer Center
NCT04308759
Increasing Access to Smoking Cessation and Smoke Free Home Services for Low-Income Pregnant Women in Northeast Texas
M.D. Anderson Cancer Center
NCT05051345
Impact of E-cigarette Use on the Body
Ohio State University Comprehensive Cancer Center
NCT04972513
Evaluating the Episodic Future Thinking Intervention for Reducing Cigarette Consumption in Cigarette Smokers
Roswell Park Cancer Institute
NCT05825001
Evaluation of Canakinumab in High-Risk Former-Smokers
Peter Shields
NCT06038526
Pilot Trial of a Game Embedded in a Smartphone App for Smoking Cessation
University of California, San Francisco
NCT05227027
Electronic Cigarette Use During Pregnancy
UConn Health
NCT03480373
Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes
M.D. Anderson Cancer Center
NCT03856515
Website Smoking Cessation Intervention for the Promotion of Smoking Cessation in Low-Income Veterans
Fred Hutchinson Cancer Center
NCT04502524
Evaluating the Impact of Quitting Using Executive Function Strategy Training (QUEST) on Smoking Cessation in Homeless Young Adult Smokers
Ohio State University Comprehensive Cancer Center
NCT06745154
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cigarette Smoking-Related Carcinoma Trial Landscape
22 indexed Cigarette Smoking-Related Carcinoma studies · 12 recruiting (55%).
Phase mix: 3 late (III/IV) vs 4 early (I/II).
Top sponsor: Ohio State University Comprehensive Cancer Center (6 trials), 8 others listed. 22 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cigarette Smoking-Related Carcinoma?
PlainTrial tracks 22 US clinical trials for Cigarette Smoking-Related Carcinoma, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cigarette Smoking-Related Carcinoma?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.