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NCT04604509 · ClinicalTrials.gov registry record · Phase 4
Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial
A Phase 4 study of Cigarette Smoking-Related Carcinoma, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 2,010
- Enrollment target
- 1
- Study location
NCT04604509: Recruiting Phase 4 study of Cigarette Smoking-Related Carcinoma, sponsored by M.D. Anderson Cancer Center.
NCT04604509 is a Phase 4 study of Cigarette Smoking-Related Carcinoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 2,010 participants, above the 372-participant average among 21 other Cigarette Smoking-Related Carcinoma trials with a reported enrollment target (440% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04604509, a Phase 4 study of Cigarette Smoking-Related Carcinoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 2,010 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase IV trial investigates how to personalize treatments (such as medications and/or counseling) for quitting smoking based on the unique character traits of participants. Nicotine replacement therapy, counseling, and/or drugs such as varenicline and bupropion may help participants quit smoking or change smoking behavior. This trial may also help doctors individualize smoking cessation treatment for participants who do not quit smoking after the first course of treatment.
Primary Outcome
Will use Bayesian statistical methods to estimate these effects and their accompanying posterior probabilities.
Conditions Studied
Interventions
- OTHER Questionnaire Administration
- DRUG Varenicline
- DRUG Bupropion Hydrochloride Controlled-release
- DRUG Nicotine Replacement
- OTHER Tobacco Cessation Counseling
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,010 participants |
| Start Date | 2020-08-04 |
| Est. Completion | 2028-12-31 |
| Phase | Phase 4 |
What NCT04604509 shows while recruiting
NCT04604509 is an interventional study that assigns participants to a tested intervention. Its 2,010 participants enrollment target places it among the larger protocols in the corpus, above the 372-participant average among 21 other Cigarette Smoking-Related Carcinoma trials with a reported enrollment target (440% higher).
The record links to 1 condition, with Cigarette Smoking-Related Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Questionnaire Administration is the first listed.
NCT04604509 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04604509 about?
NCT04604509 is a clinical study titled "Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial". This phase IV trial investigates how to personalize treatments (such as medications and/or counseling) for quitting smoking based on the unique character traits of participants. Nicotine replacement therapy, counseling, and/or drugs such as varenicline and bupropion may help participants quit smokin...
What is the current status of trial NCT04604509?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 2,010 participants. The study started on 2020-08-04. Estimated completion is 2028-12-31.
What conditions does trial NCT04604509 study?
This clinical trial studies the following conditions: Cigarette Smoking-Related Carcinoma.
What interventions are being tested in trial NCT04604509?
The interventions under investigation include: Questionnaire Administration (OTHER), Varenicline (DRUG), Bupropion Hydrochloride Controlled-release (DRUG), Nicotine Replacement (DRUG), Tobacco Cessation Counseling (OTHER).
Who is sponsoring clinical trial NCT04604509?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04604509 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cigarette Smoking-Related Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04604509's enrollment target sits among peer trials
2,010 1st of 21 higher than 21 of 21 other Cigarette Smoking-Related Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cigarette Smoking-Related Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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