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NCT06816459 · ClinicalTrials.gov registry record · Early Phase 1

Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults

A Early Phase 1 study of Cigarette Smoking-Related Carcinoma, sponsored by Roswell Park Cancer Institute.

Recruiting
Registry status
Early Phase 1
Development phase
30
Enrollment target
1
Study location

NCT06816459 is a Early Phase 1 study of Cigarette Smoking-Related Carcinoma that is actively recruiting participants, run by Roswell Park Cancer Institute. The registered enrollment target is 30 participants, below the 466-participant average among 21 other Cigarette Smoking-Related Carcinoma trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06816459, a Early Phase 1 study of Cigarette Smoking-Related Carcinoma, is actively recruiting participants, sponsored by Roswell Park Cancer Institute.

RECRUITING
Registry status
Early Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States. Flavors such as menthol play an important role in the start and continued use of tobacco products. Two ways users experience flavor is through smell and taste. Menthol has cooling and numbing properties that can increase perceptions of smoothness and reduce the perceived harshness of smoke. Menthol adds a taste and aroma commonly described as "minty". The effect of menthol flavoring on smoking behavior has been studied. Use of menthol cigarettes has been associated with greater nicotine dependence and is associated with both fewer quit attempts and lower odds of quit success. In 2022, the Food and Drug Administration proposed to restrict the use of menthol as a flavor in cigarettes. Menthol has already been banned in Canada, the United Kingdom and the European Union. In late 2022, a restriction on all flavored tobacco products went into effect in California (CA), prompting the tobacco industry to introduce substitute products that did not contain menthol. It is important to find out whether New York (NY) adult smokers who smoke menthol cigarettes can identify and characterize flavors in the same cigarette brand as sold in NY versus CA following the ban of menthol cigarettes in 2022.

Interventions

  • OTHER Cigarette smell test
  • OTHER Cigarette Taste Test
  • OTHER Study questionnaires

Study Locations (1)

New York

  • Roswell Park Cancer Institute - Buffalo

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-10-14
Est. Completion 2026-02-28
Phase Early Phase 1

Sponsor

Roswell Park Cancer Institute

365 total trials

What the Registry Record Tells You About NCT06816459

The ClinicalTrials.gov registry entry for NCT06816459 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 466-participant average among 21 other Cigarette Smoking-Related Carcinoma trials with a reported enrollment target (94% lower). The listed sponsor is Roswell Park Cancer Institute, which has 365 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cigarette Smoking-Related Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Cigarette smell test is the first listed.

NCT06816459 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06816459 about?

NCT06816459 is a clinical study titled "Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults". This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States. Flavors such as menthol play an important role in the start and continued use of tobacco products. Two ways users exp...

What is the current status of trial NCT06816459?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2025-10-14. Estimated completion is 2026-02-28.

What conditions does trial NCT06816459 study?

This clinical trial studies the following conditions: Cigarette Smoking-Related Carcinoma.

What interventions are being tested in trial NCT06816459?

The interventions under investigation include: Cigarette smell test (OTHER), Cigarette Taste Test (OTHER), Study questionnaires (OTHER).

Who is sponsoring clinical trial NCT06816459?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06816459 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.