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ClinicalTrials.gov 139 recruiting now early-phase tilt #29 of 28,707 conditions

Chronic Pain: early-phase trial registry

139 of 302 indexed Chronic Pain trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #29 of 28,707 conditions by registered trial count.

302 US clinical trials · 139 currently recruiting · #29 of 28,707 conditions by registered trial count

Chronic Pain: 302 US clinical trials tracked, 139 recruiting.

Chronic Pain is the subject of 302 registered US clinical trials on ClinicalTrials.gov, 139 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 41 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 16 of these trials.

Enrollment posture brief

Registry condition chronic-pain

OPEN 139 | RECR 46% | LATE 15 | EARLY 41 | RANK #29 | SPON 16

Nearest open-share peer: Recurrent Glioblastoma (46% recruiting · 63 trials)

Chronic Pain (this)46%Parkinson Disease45.3%Cardiovascular Diseases44.1%HIV35.9%COVID-1922.7%
Open-enrollment share among volume-matched conditions near Chronic Pain

Chronic Pain lists 139 open slots (46% of 302 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Pain is recruiting above its size-band peers.

    139 of 302 indexed trials (46%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Chronic Pain trials is spread across many organizations.

    VA Office of Research and Development accounts for 16 of 302 trials (5.3%). 155 distinct sponsors appear on at least one study for this condition label.

  3. Typical Chronic Pain enrolment sits around 80 participants.

    Median target enrolment is 80 among the 302 trials that report a genuine target (sentinel values excluded). 164 of those (54.3%) plan for fewer than 100 participants.

  4. Chronic Pain research is mostly interventional.

    260 interventional and 42 observational studies make up this index (86.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 119Phase 222Phase 37Phase 48

Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 22
Phase 3 7
Phase 4 8

Named interventions

Most-linked intervention names on Chronic Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
11 trials
Placebo Other
5 trials
Ketamine Drug
4 trials
Quantitative Sensory Test 3 Diagnostic test
3 trials
Quantitative Sensory Test 2 Diagnostic test
3 trials
Quantitative Sensory Test 1 Diagnostic test
3 trials
Oxytocin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials

US sites by state

Facility locations filed on Chronic Pain trials. A trial with sites in several states counts in each.

California 56 trials
Massachusetts 31 trials
New York 27 trials
Florida 27 trials
North Carolina 25 trials
Michigan 23 trials
Washington 21 trials
Illinois 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Pain page

302 registered trials, 139 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Pain condition card totals 302 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.