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ClinicalTrials.gov 10 recruiting now official registry

Chronic Myelogenous Leukemia clinical trials

Every US clinical trial registered for Chronic Myelogenous Leukemia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

30 US clinical trials · 10 currently recruiting

The research picture

Chronic Myelogenous Leukemia has 30 registered US clinical trials, 10 of them open to new participants right now — about 33% of the total.

10
recruiting participants now
33%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
4
top sponsor: Masonic Cancer Center, University of Minnesota

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 3,000 participants

Chart Review Study of Chronic Myelogenous Leukemia (CML) Patients Treated With Imatinib Outside of a Clinical Trial

M.D. Anderson Cancer Center

NCT00816114

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING Phase 4 347 participants

Asciminib Roll-over Study

Novartis Pharmaceuticals

NCT04877522

RECRUITING Phase 2 300 participants

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

Masonic Cancer Center, University of Minnesota

NCT03314974

RECRUITING NA 200 participants

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT01962636

RECRUITING Phase 1 90 participants

TGRX-678 US Phase I for Subjects with Refractory or Advanced Chronic Myelogenous Leukemia

Shenzhen TargetRx Co.

NCT06088888

RECRUITING Phase 1 60 participants

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Stanford University

NCT05088356

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

ACTIVE NOT RECRUITING Phase 2 300 participants

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Center for International Blood and Marrow Transplant Research

NCT04904588

ACTIVE NOT RECRUITING Phase 2 22 participants

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Masonic Cancer Center, University of Minnesota

NCT03674411

ACTIVE NOT RECRUITING Phase 1 15 participants

Administration of Donor T Cells With the Caspase-9 Suicide Gene

Baylor College of Medicine

NCT01494103

COMPLETED Phase 1 507 participants

A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Novartis Pharmaceuticals

NCT00109707

COMPLETED Phase 2 279 participants

Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

National Heart, Lung, and Blood Institute (NHLBI)

NCT02208037

COMPLETED Phase 2 215 participants

Nilotinib Treatment-free Remission Study in CML (Chronic Myeloid Leukemia) Patients

Novartis Pharmaceuticals

NCT01784068

COMPLETED Phase 2 202 participants

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00003838

COMPLETED 119 participants

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

Notable Labs

NCT04014764

COMPLETED Phase 2 73 participants

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Fred Hutchinson Cancer Center

NCT00723099

COMPLETED Phase 4 52 participants

An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib Treatment

Novartis Pharmaceuticals

NCT00980018

COMPLETED Phase 1 52 participants

ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies

AbbVie (prior sponsor, Abbott)

NCT01110473

COMPLETED Phase 2 51 participants

INCB018424 in Patients With Advanced Hematologic Malignancies

M.D. Anderson Cancer Center

NCT00674479

COMPLETED Phase 2 46 participants

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Baylor College of Medicine

NCT00368355

COMPLETED Phase 1 43 participants

Improving Blood Stem Cell Collection and Transplant Procedures

National Heart, Lung, and Blood Institute (NHLBI)

NCT01517035

COMPLETED Phase 2 40 participants

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Accelerated Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Astex Pharmaceuticals

NCT00041990

COMPLETED Phase 2 30 participants

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT00144677

COMPLETED Phase 2 25 participants

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Northside Hospital

NCT02581007

COMPLETED Phase 1 10 participants

Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood Cancers

ViaCell

NCT00089596

COMPLETED Phase 2 10 participants

Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to Gleevec

Bayer

NCT00661180

COMPLETED Phase 2 6 participants

Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATG

M.D. Anderson Cancer Center

NCT01390402

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 16
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Chronic Myelogenous Leukemia Trial Landscape

ClinicalTrials.gov lists 30 US studies indexed under Chronic Myelogenous Leukemia, and 10 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Chronic Myelogenous Leukemia shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 23 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Chronic Myelogenous Leukemia is led by Masonic Cancer Center, University of Minnesota with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 30 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Chronic Myelogenous Leukemia?

PlainTrial tracks 30 US clinical trials for Chronic Myelogenous Leukemia, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Chronic Myelogenous Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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