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ClinicalTrials.gov 10 recruiting now early-phase tilt

Chronic Myelogenous Leukemia: early-phase trial registry

10 of 30 indexed Chronic Myelogenous Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #519 of 28,707 conditions by registered trial count.

30 US clinical trials · 10 currently recruiting · #519 of 28,707 conditions by registered trial count

Chronic Myelogenous Leukemia: 30 US clinical trials tracked, 10 recruiting.

Chronic Myelogenous Leukemia is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most active sponsor is Masonic Cancer Center, University of Minnesota, running 4 of these trials.

Enrollment posture brief

Registry condition chronic-myelogenous-leukemia

OPEN 10 | RECR 33% | LATE 2 | EARLY 23 | RANK #519 | SPON 4

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

AML60%Acute Myeloid Leukemia40%Chronic Myelogenous Leuk (th…33%Anatomic Stage IA Breast Can26.7%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Chronic Myelogenous Leukemia

Chronic Myelogenous Leukemia lists 10 open slots (33% of 30 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Myelogenous Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Myelogenous Leukemia is recruiting below its size-band peers.

    10 of 30 indexed trials (33.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Chronic Myelogenous Leukemia trials is spread across many organizations.

    Masonic Cancer Center, University of Minnesota accounts for 4 of 30 trials (13.3%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Chronic Myelogenous Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 56 among the 30 trials that report a genuine target (sentinel values excluded). 19 of those (63.3%) plan for fewer than 100 participants.

  4. Chronic Myelogenous Leukemia research is mostly interventional.

    26 interventional and 4 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 216Phase 42

Open and recent trials

30 total, page 1 of 1

RECRUITING 3,000 participants

Chart Review Study of Chronic Myelogenous Leukemia (CML) Patients Treated With Imatinib Outside of a Clinical Trial

M.D. Anderson Cancer Center

NCT00816114

RECRUITING 2,000 participants

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

Wake Forest University Health Sciences

NCT01890486

RECRUITING Phase 4 347 participants

Asciminib Roll-over Study

Novartis Pharmaceuticals

NCT04877522

RECRUITING Phase 2 300 participants

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

Masonic Cancer Center, University of Minnesota

NCT03314974

RECRUITING NA 200 participants

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT01962636

RECRUITING Phase 1 90 participants

TGRX-678 US Phase I for Subjects with Refractory or Advanced Chronic Myelogenous Leukemia

Shenzhen TargetRx Co.

NCT06088888

RECRUITING Phase 1 60 participants

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Stanford University

NCT05088356

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

ACTIVE NOT RECRUITING Phase 2 300 participants

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Center for International Blood and Marrow Transplant Research

NCT04904588

ACTIVE NOT RECRUITING Phase 2 22 participants

Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy

Masonic Cancer Center, University of Minnesota

NCT03674411

ACTIVE NOT RECRUITING Phase 1 15 participants

Administration of Donor T Cells With the Caspase-9 Suicide Gene

Baylor College of Medicine

NCT01494103

COMPLETED Phase 1 507 participants

A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Novartis Pharmaceuticals

NCT00109707

COMPLETED Phase 2 279 participants

Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

National Heart, Lung, and Blood Institute (NHLBI)

NCT02208037

COMPLETED Phase 2 215 participants

Nilotinib Treatment-free Remission Study in CML (Chronic Myeloid Leukemia) Patients

Novartis Pharmaceuticals

NCT01784068

COMPLETED Phase 2 202 participants

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00003838

COMPLETED 119 participants

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

Notable Labs

NCT04014764

COMPLETED Phase 2 73 participants

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Fred Hutchinson Cancer Center

NCT00723099

COMPLETED Phase 4 52 participants

An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib Treatment

Novartis Pharmaceuticals

NCT00980018

COMPLETED Phase 1 52 participants

ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies

AbbVie (prior sponsor, Abbott)

NCT01110473

COMPLETED Phase 2 51 participants

INCB018424 in Patients With Advanced Hematologic Malignancies

M.D. Anderson Cancer Center

NCT00674479

COMPLETED Phase 2 46 participants

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Baylor College of Medicine

NCT00368355

COMPLETED Phase 1 43 participants

Improving Blood Stem Cell Collection and Transplant Procedures

National Heart, Lung, and Blood Institute (NHLBI)

NCT01517035

COMPLETED Phase 2 40 participants

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Accelerated Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Astex Pharmaceuticals

NCT00041990

COMPLETED Phase 2 30 participants

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT00144677

COMPLETED Phase 2 25 participants

Reduced Intensity Conditioning Transplant Using Haploidentical Donors

Northside Hospital

NCT02581007

COMPLETED Phase 1 10 participants

Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood Cancers

ViaCell

NCT00089596

COMPLETED Phase 2 10 participants

Open Label Phase II Study of BAY 43-9006 in Chronic Myelogenous Leukemia (CML) Patients Resistant to Gleevec

Bayer

NCT00661180

COMPLETED Phase 2 6 participants

Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATG

M.D. Anderson Cancer Center

NCT01390402

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 16
Phase 4 2

Named interventions

Most-linked intervention names on Chronic Myelogenous Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Drug
7 trials
Cyclophosphamide Drug
7 trials
Nilotinib Drug
3 trials
Total Body Irradiation Radiation
3 trials
Cyclosporine Drug
2 trials
Busulfan Drug
2 trials
Melphalan Drug
2 trials
decitabine (5-aza-2'deoxycytidine) Drug
1 trials

US sites by state

Facility locations filed on Chronic Myelogenous Leukemia trials. A trial with sites in several states counts in each.

Texas 11 trials
New York 8 trials
Minnesota 8 trials
California 7 trials
Maryland 6 trials
Florida 6 trials
Colorado 6 trials
Oregon 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Myelogenous Leukemia page

30 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Myelogenous Leukemia condition card totals 30 registered trials; most-linked intervention Fludarabine; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.