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Chronic Heart Failure: early-phase trial registry
5 of 13 indexed Chronic Heart Failure trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,315 of 28,707 conditions by registered trial count.
13 US clinical trials · 5 currently recruiting · #1,315 of 28,707 conditions by registered trial count
Chronic Heart Failure: 13 US clinical trials tracked, 5 recruiting.
Chronic Heart Failure is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Nile Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition chronic-heart-failure
OPEN 5 | RECR 38% | LATE 1 | EARLY 3 | RANK #1315 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)
Chronic Heart Failure lists 5 open slots (38% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Chronic Heart Failure on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Chronic Heart Failure is recruiting below its size-band peers.
5 of 13 indexed trials (38.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Chronic Heart Failure trials is spread across many organizations.
Nile Therapeutics accounts for 1 of 13 trials (7.7%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Chronic Heart Failure enrolment sits around 150 participants.
Median target enrolment is 150 among the 13 trials that report a genuine target (sentinel values excluded). 4 of those (30.8%) plan for fewer than 100 participants.
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Chronic Heart Failure research is mostly interventional.
10 interventional and 3 observational studies make up this index (76.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
13 total, page 1 of 1
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
Pharmacosmos A/S
NCT06929806
The HEARTFELT Study
Heartfelt Technologies
NCT06222099
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
XSpline S.p.A.
NCT05327062
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
Beth Israel Deaconess Medical Center
NCT05934565
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
AquaPass Medical
NCT06360380
Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction
Akros Pharma
NCT06017609
Destination Therapy Post Approval Study
Medtronic Cardiac Rhythm and Heart Failure
NCT03681210
R&D Study to Evaluate Cordio's Usability and to Collect Patient Speech Utterances
Cordio Medical
NCT05876533
Cost and Shared Decision-Making for Heart Failure
Emory University
NCT04793880
Telehealth Management in HF Disparity Patients
Northwell Health
NCT02196922
Iron Deficiency and FGF23 Regulation in CKD and HF
Northwestern University
NCT03106298
PK/PD Study of Subcutaneous Cenderitide Infusion in CHF Patients
Nile Therapeutics
NCT01316432
A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00094562
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Chronic Heart Failure records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Chronic Heart Failure trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Chronic Heart Failure page
13 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Chronic Heart Failure trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Nile Therapeutics sponsors the most Chronic Heart Failure trials on record, review their full trial history before evaluating a specific study. See Nile Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Heart Failure condition card totals 13 registered trials; most-linked intervention Fish oil supplement; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.