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NCT06017609 · ClinicalTrials.gov registry record · Phase 2

Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction

A Phase 2 study of Chronic Heart Failure, sponsored by Akros Pharma.

Active
Registry status
Phase 2
Development phase
314
Enrollment target
20
Study locations

NCT06017609 is a Phase 2 study of Chronic Heart Failure that is active but no longer recruiting, run by Akros Pharma. The registered enrollment target is 314 participants, below the 396-participant average among 12 other Chronic Heart Failure trials with a reported enrollment target (21% lower). The trial reports 20 study locations across 11 states.

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The verdict

NCT06017609, a Phase 2 study of Chronic Heart Failure, is active but no longer recruiting, sponsored by Akros Pharma.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
314 participants
Enrollment target
20
Study locations

Study Summary

This study will evaluate the efficacy, safety, tolerability and pharmacokinetics of JTT-861 administered once daily for 12 weeks in subjects with heart failure with reduced ejection fraction (HFrEF) who are on a stable, guideline-directed medical therapy for heart failure.

Conditions Studied

Interventions

  • DRUG Placebo Capsules
  • DRUG JTT-861 Capsules

Study Locations (20)

Florida

  • Nature Coast Clinical Research - Crystal River
  • Indago Research & Health Center, Inc. - Hialeah
  • Med Research of Florida - Miami
  • Pharma Medical Innovation, Inc. - Miami Lakes
  • Floridian Clinical Research - Miami Lakes

Texas

  • NextStage Clinical Research-Beaumont- (01) - Beaumont
  • Cypress Heart and Vascular Center - Cypress
  • NextStage Clinical Research-Port Arthur-(02) - Port Arthur
  • Sherman Clinical Research - Sherman
  • Waco Cardiology Associates - NextStage Clinical Research - Waco

Michigan

  • Henry Ford Hospital - Detroit
  • Profound Research LLC - Farmington Hills

Arizona

  • Arensia Exploratory Medicine Inc. - Phoenix

Illinois

  • Affinity Health - Park Ridge

Indiana

  • ASHA Clinical Research-Munster, LLC - Hammond

Louisiana

  • Monroe Research, LLC - West Monroe

Missouri

  • NextStage Clinical Research - (Kansas City [01]) - Kansas City

Trial Details

FieldValue
Enrollment Target 314 participants
Start Date 2023-12-20
Est. Completion 2026-12
Phase Phase 2

Sponsor

Akros Pharma

18 total trials

What the Registry Record Tells You About NCT06017609

The ClinicalTrials.gov registry entry for NCT06017609 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 314 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 396-participant average among 12 other Chronic Heart Failure trials with a reported enrollment target (21% lower). The listed sponsor is Akros Pharma, which has 18 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo Capsules is the first listed.

NCT06017609 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Florida, Texas, Michigan.

Frequently Asked Questions

What is clinical trial NCT06017609 about?

NCT06017609 is a clinical study titled "Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction". This study will evaluate the efficacy, safety, tolerability and pharmacokinetics of JTT-861 administered once daily for 12 weeks in subjects with heart failure with reduced ejection fraction (HFrEF) who are on a stable, guideline-directed medical therapy for heart failure.

What is the current status of trial NCT06017609?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 314 participants. The study started on 2023-12-20. Estimated completion is 2026-12.

What conditions does trial NCT06017609 study?

This clinical trial studies the following conditions: Chronic Heart Failure.

What interventions are being tested in trial NCT06017609?

The interventions under investigation include: Placebo Capsules (DRUG), JTT-861 Capsules (DRUG).

Who is sponsoring clinical trial NCT06017609?

This trial is sponsored by Akros Pharma, which has 18 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06017609 being conducted?

This trial has 20 study locations across Arizona, Florida, Illinois, Indiana, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.