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NCT03681210 · ClinicalTrials.gov registry record
Destination Therapy Post Approval Study
A clinical trial of Chronic Heart Failure, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
- Active
- Registry status
- 300
- Enrollment target
- 20
- Study locations
NCT03681210: Active study of Chronic Heart Failure, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
NCT03681210 is a study of Chronic Heart Failure that is active but no longer recruiting, run by Medtronic Cardiac Rhythm and Heart Failure. The registered enrollment target is 300 participants, below the 397-participant average among 12 other Chronic Heart Failure trials with a reported enrollment target (24% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03681210, a study of Chronic Heart Failure, is active but no longer recruiting, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
- ACTIVE NOT RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 20
- Study locations
Study Summary
Medtronic is sponsoring the HeartWare™ HVAD™ Destination Therapy (DT) Post Approval Study (PAS) to further confirm safety and effectiveness of the HeartWare Ventricular Assist Device System (HVAD System) when used as intended, in "real-world" clinical practice. The Destination Therapy Post Approval Study (DT PAS) is conducted within Medtronic's Product Surveillance Platform.
Primary Outcome
Complications include death, disabling stroke, or device malfunction or failure requiring exchange, explantation or urgent transplantation.
Conditions Studied
Interventions
- DEVICE HeartWare Ventricular Assist Device
Study Locations (20)
Florida
- University of Miami - Coral Gables
- Mayo Clinic (Jacksonville FL) - Jacksonville
- AdventHealth - Orlando
- University of South Florida Health - Tampa
California
- University of California San Diego - San Diego
- University of California San Francisco Medical Center - San Francisco
- Stanford University Hospital - Stanford
Illinois
- Northwestern University - Chicago
- Loyola University - Maywood
- Advocate Christ Medical Center (Cardiac Surgery Clinical Research Center) - Oak Lawn
Maryland
- University of Maryland Medical Center - Baltimore
- The Johns Hopkins Hospital - Baltimore
Massachusetts
- Tufts Medical Center - Boston
- Massachusetts General Hospital - Boston
Arkansas
- Saint Vincent Heart Clinic Arkansas - Little Rock
Colorado
- University of Colorado - Aurora
Indiana
- Saint Vincent Medical Group - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2018-10-31 |
| Est. Completion | 2026-04 |
What the registry record for NCT03681210 still lists
NCT03681210 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 397-participant average among 12 other Chronic Heart Failure trials with a reported enrollment target (24% lower).
The record links to 1 condition, with Chronic Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which HeartWare Ventricular Assist Device is the first listed.
NCT03681210 names 20 study sites across 11 states, led by Florida, California, Illinois.
Frequently Asked Questions
What is clinical trial NCT03681210 about?
NCT03681210 is a clinical study titled "Destination Therapy Post Approval Study". Medtronic is sponsoring the HeartWare™ HVAD™ Destination Therapy (DT) Post Approval Study (PAS) to further confirm safety and effectiveness of the HeartWare Ventricular Assist Device System (HVAD System) when used as intended, in "real-world" clinical practice. The Destination Therapy Post Approval...
What is the current status of trial NCT03681210?
This trial is currently active not recruiting. The enrollment target is 300 participants. The study started on 2018-10-31. Estimated completion is 2026-04.
What conditions does trial NCT03681210 study?
This clinical trial studies the following conditions: Chronic Heart Failure.
What interventions are being tested in trial NCT03681210?
The interventions under investigation include: HeartWare Ventricular Assist Device (DEVICE).
Who is sponsoring clinical trial NCT03681210?
This trial is sponsored by Medtronic Cardiac Rhythm and Heart Failure, which has 115 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03681210 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03681210's enrollment target sits among peer trials
300 4th of 12 higher than 9 of 12 other Chronic Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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