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NCT02346903 · ClinicalTrials.gov registry record · NA
Chest Pain Perception and Capsaicin Sensitivity
A NA study of Chest Pain, sponsored by Bassett Healthcare.
- Completed
- Registry status
- NA
- Development phase
- 99
- Enrollment target
- 1
- Study location
NCT02346903: Completed NA study of Chest Pain, sponsored by Bassett Healthcare.
NCT02346903 is a NA study of Chest Pain that has completed, run by Bassett Healthcare. The registered enrollment target is 99 participants, below the 1,454-participant average among 22 other Chest Pain trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02346903, a NA study of Chest Pain, has completed, sponsored by Bassett Healthcare.
- COMPLETED
- Registry status
- NA
- Development phase
- 99 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether there is a positive correlation between the ability to sense chest pain in the context of myocardial ischemia and the ability to sense discomfort associated with the topical application of the TRPV1 agonist capsaicin (the active ingredient on hot chili peppers). Patients undergoing clinical elective balloon angioplasty of a coronary stenosis will be asked to quantify the subjective intensity of any chest pain they feel during a standardized episode of myocardial ischemia produced by a one-minute coronary balloon occlusion, using a previously-validated numeric rating scale. The same patients will subsequently be asked to grade the subjective intensity of cutaneous discomfort resulting from application of a capsaicin-containing patch (Capzasin-HP Cream, an over-the-counter product approved for topical application to treat muscle and joint aches) to the forearm. The goal will be to determine whether an association can be demonstrated between the subjective perception of ischemic chest pain during coronary balloon occlusion and cutaneous capsaicin sensitivity. Such an association could have considerable clinical value, as it might allow physicians to prospectively assess an individual's ability to perceive myocardial ischemia/infarction by assessing his/her subjective response to the topical application of capsaicin.
Primary Outcome
Each patient will be asked to rate their discomfort at the application site based on a 10 point numerical rating scale for cutaneous discomfort, ranging from 0 ("no discomfort") to 10 ("the worst discomfort imaginable")
Conditions Studied
Interventions
- DRUG Capsaicin
Study Locations (1)
New York
- Bassett Healthcare Network - Cooperstown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 99 participants |
| Start Date | 2013-04 |
| Est. Completion | 2015-08 |
| Phase | NA |
What the finished NCT02346903 record still lists
NCT02346903 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 99 participants, a relatively small participant target, below the 1,454-participant average among 22 other Chest Pain trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Chest Pain appearing as the primary indexed condition, and to 1 intervention - of which Capsaicin is the first listed.
NCT02346903 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02346903 about?
NCT02346903 is a clinical study titled "Chest Pain Perception and Capsaicin Sensitivity". The purpose of this study is to determine whether there is a positive correlation between the ability to sense chest pain in the context of myocardial ischemia and the ability to sense discomfort associated with the topical application of the TRPV1 agonist capsaicin (the active ingredient on hot chi...
What is the current status of trial NCT02346903?
This trial is currently completed. It is a NA study. The enrollment target is 99 participants. The study started on 2013-04. Estimated completion is 2015-08.
What conditions does trial NCT02346903 study?
This clinical trial studies the following conditions: Chest Pain.
What interventions are being tested in trial NCT02346903?
The interventions under investigation include: Capsaicin (DRUG).
Who is sponsoring clinical trial NCT02346903?
This trial is sponsored by Bassett Healthcare, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02346903 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chest Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02346903's enrollment target sits among peer trials
99 17th of 22 higher than 6 of 22 other Chest Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chest Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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