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NCT05353985 · ClinicalTrials.gov registry record · Phase 2

A Study of TAK-062 in Treatment of Active Celiac Disease in Participants Attempting a Gluten-Free Diet

A Phase 2 study of Celiac Disease, sponsored by Takeda.

Completed
Registry status
Phase 2
Development phase
153
Enrollment target
20
Study locations

NCT05353985 is a Phase 2 study of Celiac Disease that has completed, run by Takeda. The registered enrollment target is 153 participants, below the 1,974-participant average among 24 other Celiac Disease trials with a reported enrollment target (92% lower). The trial reports 20 study locations across 6 states.

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The verdict

NCT05353985, a Phase 2 study of Celiac Disease, has completed, sponsored by Takeda.

COMPLETED
Registry status
Phase 2
Development phase
153 participants
Enrollment target
20
Study locations

Study Summary

The main aim is to see how TAK-062 works to reduce celiac-related symptoms and improve small intestinal damage due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in treated participants versus placebo controls.

Conditions Studied

Interventions

  • DRUG TAK-062
  • DIETARY_SUPPLEMENT Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar
  • DRUG TAK-062 Placebo
  • DIETARY_SUPPLEMENT Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bar

Study Locations (20)

California

  • Gastroenterology and Liver Institute - Escondido
  • Om Research LLC - Lancaster
  • So. California Research Institute Med Group Inc./West Gastroenterology Med Group - Los Angeles
  • UCLA - Los Angeles
  • Providence Facey Medical Foundation - Mission Hills
  • Stanford University School of Medicine - Redwood City
  • Medical Associates Research Group, Inc. - San Diego

Arizona

  • Research Solutions of Arizona, PC - Litchfield Park
  • One of a Kind Clinical Research Center LLC - Paradise Valley
  • Mayo Clinic- Arizona - Scottsdale
  • GI Alliance- Sun City - Sun City
  • Adobe Clinical Research LLC - Tucson

Florida

  • Nature Coast Clinical Research, LLC - Inverness
  • University of Miami Medical Center - Miami
  • Wellness Clinical Research - Miami Lakes
  • Gastroenterology Associates of Pensacola, PA - Pensacola

Connecticut

  • Medical Research Center of Connecticut, LLC 300143562 - Hamden
  • Central Connecticut Endoscopy Center - Plainville

Alabama

  • University of Alabama at Birmingham - Birmingham

Colorado

  • Asthma and Allergy Associates, PC - Colorado Springs

Trial Details

FieldValue
Enrollment Target 153 participants
Start Date 2022-06-30
Est. Completion 2024-11-06
Phase Phase 2

Sponsor

Takeda

408 total trials

What the Registry Record Tells You About NCT05353985

The ClinicalTrials.gov registry entry for NCT05353985 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 153 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,974-participant average among 24 other Celiac Disease trials with a reported enrollment target (92% lower). The listed sponsor is Takeda, which has 408 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Celiac Disease appearing as the primary indexed condition, and to 4 interventions - of which TAK-062 is the first listed.

NCT05353985 reports 20 study locations spanning 6 distinct geographic areas - top geographies include California, Arizona, Florida.

Frequently Asked Questions

What is clinical trial NCT05353985 about?

NCT05353985 is a clinical study titled "A Study of TAK-062 in Treatment of Active Celiac Disease in Participants Attempting a Gluten-Free Diet". The main aim is to see how TAK-062 works to reduce celiac-related symptoms and improve small intestinal damage due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in treated participants versus placebo controls.

What is the current status of trial NCT05353985?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 153 participants. The study started on 2022-06-30. Estimated completion is 2024-11-06.

What conditions does trial NCT05353985 study?

This clinical trial studies the following conditions: Celiac Disease.

What interventions are being tested in trial NCT05353985?

The interventions under investigation include: TAK-062 (DRUG), Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar (DIETARY_SUPPLEMENT), TAK-062 Placebo (DRUG), Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bar (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT05353985?

This trial is sponsored by Takeda, which has 408 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05353985 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.