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ClinicalTrials.gov 3 recruiting now official registry

Cardiopulmonary Bypass clinical trials

3 of 11 indexed Cardiopulmonary Bypass trials are currently recruiting.

11 US clinical trials · 3 currently recruiting

Cardiopulmonary Bypass is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Xijing Hospital, running 1 of these trials.

The research picture

Cardiopulmonary Bypass has 11 registered US clinical trials, 3 of them open to new participants right now, about 27% of the total.

3
recruiting participants now
27%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
1
top sponsor: Xijing Hospital
Phase 11Phase 21Phase 33

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 3 3,650 participants

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass

Xijing Hospital

NCT06702553

RECRUITING 150 participants

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

University of Maryland, Baltimore

NCT05189262

RECRUITING 56 participants

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Sophia Koutsogiannaki

NCT04296071

ACTIVE NOT RECRUITING Phase 3 736 participants

ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

Alexion Pharmaceuticals

NCT05746559

COMPLETED Phase 2 785 participants

Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery

University of Arkansas

NCT00569855

COMPLETED Phase 1 504 participants

Understanding "Heparin Resistance" in Cardiac Surgery

Massachusetts General Hospital

NCT01598883

COMPLETED NA 460 participants

Cerebral Autoregulation Monitoring During Cardiac Surgery

Northwestern University

NCT00981474

COMPLETED 290 participants

Aprotinin in Neonates Undergoing Cardiopulmonary Bypass

Children's Healthcare of Atlanta

NCT00469742

COMPLETED 40 participants

SPY Imaging System: Its Role in Pediatric Cardiac Surgery

Emory University

NCT00446927

COMPLETED NA 30 participants

Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass

Vanderbilt University Medical Center

NCT01228305

COMPLETED Phase 3

Safety and Hemostatic Efficacy of Fibrin Sealant Vapor Heated, Solvent/Detergent Treated (FS VH S/D) Compared With Currently Licensed TISSEEL VH Fibrin Sealant in Subjects Undergoing Cardiac Surgery

Baxter Healthcare Corporation

NCT00161733

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cardiopulmonary Bypass Trial Landscape

11 indexed Cardiopulmonary Bypass studies · 3 recruiting (27%).

Phase mix: 3 late (III/IV) vs 2 early (I/II).

Top sponsor: Xijing Hospital (1 trial), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cardiopulmonary Bypass?

PlainTrial tracks 11 US clinical trials for Cardiopulmonary Bypass, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cardiopulmonary Bypass?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.