Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04296071 · ClinicalTrials.gov registry record
Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)
A clinical trial of Cardiopulmonary Bypass and Lung Injury, sponsored by Sophia Koutsogiannaki.
- Recruiting
- Registry status
- 56
- Enrollment target
- 1
- Study location
NCT04296071: Recruiting study of Cardiopulmonary Bypass and Lung Injury, sponsored by Sophia Koutsogiannaki.
NCT04296071 is a study of Cardiopulmonary Bypass and Lung Injury that is actively recruiting participants, run by Sophia Koutsogiannaki. The registered enrollment target is 56 participants, below the 695-participant average among 10 other Cardiopulmonary Bypass trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04296071, a study of Cardiopulmonary Bypass and Lung Injury, is actively recruiting participants, sponsored by Sophia Koutsogiannaki.
- RECRUITING
- Registry status
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.
Primary Outcome
We will analyze neutrophil profiles in the blood and tracheal aspirates
Conditions Studied
Interventions
- OTHER Research study
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2022-10-14 |
| Est. Completion | 2026-12 |
What NCT04296071 shows while recruiting
NCT04296071 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 695-participant average among 10 other Cardiopulmonary Bypass trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Cardiopulmonary Bypass appearing as the primary indexed condition, and to 1 intervention - of which Research study is the first listed.
NCT04296071 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04296071 about?
NCT04296071 is a clinical study titled "Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)". Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.
What is the current status of trial NCT04296071?
This trial is currently recruiting. The enrollment target is 56 participants. The study started on 2022-10-14. Estimated completion is 2026-12.
What conditions does trial NCT04296071 study?
This clinical trial studies the following conditions: Cardiopulmonary Bypass, Lung Injury.
What interventions are being tested in trial NCT04296071?
The interventions under investigation include: Research study (OTHER).
Who is sponsoring clinical trial NCT04296071?
This trial is sponsored by Sophia Koutsogiannaki, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04296071 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiopulmonary Bypass
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04296071's enrollment target sits among peer trials
56 9th of 10 higher than 2 of 10 other Cardiopulmonary Bypass trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiopulmonary Bypass trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Cardiopulmonary Bypass Induced Red Blood Cell Lysis
RECRUITING
-
Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass
RECRUITING · Phase 3
-
ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
ACTIVE NOT RECRUITING · Phase 3
-
Impact of Pulsatile Cardio-Pulmonary Bypass (CPB) on Vital Organ Recovery
ACTIVE NOT RECRUITING
-
SPY Imaging System: Its Role in Pediatric Cardiac Surgery
COMPLETED
-
Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02287428 · 56 participants · Phase 1
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
- NCT02923011 · 56 participants · Phase 3
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
- NCT02935283 · 56 participants
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
- NCT03375866 · 56 participants · NA
Effects of Mixed Nut Consumption on Satiety and Weight Management
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI