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NCT00981474 · ClinicalTrials.gov registry record · NA

Cerebral Autoregulation Monitoring During Cardiac Surgery

A NA study of Cardiopulmonary Bypass and Thoracic Surgery, sponsored by Northwestern University.

Completed
Registry status
NA
Development phase
460
Enrollment target
1
Study location

NCT00981474: Completed NA study of Cardiopulmonary Bypass and Thoracic Surgery, sponsored by Northwestern University.

NCT00981474 is a NA study of Cardiopulmonary Bypass and Thoracic Surgery that has completed, run by Northwestern University. The registered enrollment target is 460 participants, below the 654-participant average among 10 other Cardiopulmonary Bypass trials with a reported enrollment target (30% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00981474, a NA study of Cardiopulmonary Bypass and Thoracic Surgery, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
NA
Development phase
460 participants
Enrollment target
1
Study location

Study Summary

Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life. New strategies of care are needed to avoid rising complications for the growing number of aged patients undergoing cardiac surgery. This study will evaluate novel methods for reducing brain injury during surgery from inadequate brain blood flow using techniques that could be widely employed.

Primary Outcome

The composite neurological outcome was composed of clinical stroke, or new ischemic lesions detected on postoperative brain diffusion weighted magnetic resonance imaging(DWI), or cognitive decline from baseline to 4-6 weeks after surgery.

Interventions

  • DRUG blood pressure maintenance based on cerebral blood flow autoregulation measurement
  • DEVICE Control group

Study Locations (1)

Illinois

  • Northwestern Memorial Hospital - Chicago

Trial Details

FieldValue
Enrollment Target 460 participants
Start Date 2009-09-01
Est. Completion 2020-02-28
Phase NA
Northwestern University

1,209 total trials

What the finished NCT00981474 record still lists

NCT00981474 is an interventional study that assigns participants to a tested intervention. The registered 460 participants enrollment target is mid-sized for trials with a published cap, below the 654-participant average among 10 other Cardiopulmonary Bypass trials with a reported enrollment target (30% lower).

The record links to 2 conditions, with Cardiopulmonary Bypass appearing as the primary indexed condition, and to 2 interventions - of which blood pressure maintenance based on cerebral blood flow autoregulation measurement is the first listed.

NCT00981474 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT00981474 about?

NCT00981474 is a clinical study titled "Cerebral Autoregulation Monitoring During Cardiac Surgery". Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life. New strategies of care are needed to avoid rising complications for the growing number of aged patients undergoing cardiac...

What is the current status of trial NCT00981474?

This trial is currently completed. It is a NA study. The enrollment target is 460 participants. The study started on 2009-09-01. Estimated completion is 2020-02-28.

What conditions does trial NCT00981474 study?

This clinical trial studies the following conditions: Cardiopulmonary Bypass, Thoracic Surgery.

What interventions are being tested in trial NCT00981474?

The interventions under investigation include: blood pressure maintenance based on cerebral blood flow autoregulation measurement (DRUG), Control group (DEVICE).

Who is sponsoring clinical trial NCT00981474?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00981474 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cardiopulmonary Bypass

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00981474's enrollment target sits among peer trials

460 5th of 10 higher than 6 of 10 other Cardiopulmonary Bypass trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cardiopulmonary Bypass trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00981474, the US trial registry maintained by the National Library of Medicine. NCT00981474 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.