Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04090424 · ClinicalTrials.gov registry record · NA
Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns
A NA study of Burns, sponsored by PolyNovo Biomaterials Pty.
- Active
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 20
- Study locations
NCT04090424: Active NA study of Burns, sponsored by PolyNovo Biomaterials Pty.
NCT04090424 is a NA study of Burns that is active but no longer recruiting, run by PolyNovo Biomaterials Pty. The registered enrollment target is 150 participants, above the 79-participant average among 36 other Burns trials with a reported enrollment target (90% higher). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04090424, a NA study of Burns, is active but no longer recruiting, sponsored by PolyNovo Biomaterials Pty.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a multi-center, pivotal study to assess the safety and effectiveness of a new method of treating severe burns using NovoSorb® Biodegradable Temporizing Matrix (BTM).
Primary Outcome
Assessment of clinical outcome by wound closure
Conditions Studied
Interventions
- PROCEDURE Standard of Care
- DEVICE NovoSorb BTM
Study Locations (20)
California
- Southern California Regional Burn Center at LAC+USC - Los Angeles
- University of California Davis Medical Center - Sacramento
Massachusetts
- Brigham and Women's Hospital - Boston
- Massachusetts General Hospital - Boston
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
- Wake Forest Baptist Health - Winston-Salem
Ohio
- Akron Children's Hospital, Burn Center - Akron
- The Ohio State University/ Wexner Medical Center - Columbus
Pennsylvania
- Lehigh Valley Hospital and Health Network - Allentown
- Temple University Hospital - Philadelphia
Arizona
- Valleywise Health - Phoenix
Connecticut
- Bridgeport Hospital - Bridgeport
District of Columbia
- MedStar Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2021-09-21 |
| Est. Completion | 2026-12 |
| Phase | NA |
What the registry record for NCT04090424 still lists
NCT04090424 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 79-participant average among 36 other Burns trials with a reported enrollment target (90% higher).
The record links to 1 condition, with Burns appearing as the primary indexed condition, and to 2 interventions - of which Standard of Care is the first listed.
NCT04090424 names 20 study sites across 15 states, led by California, Massachusetts, North Carolina.
Frequently Asked Questions
What is clinical trial NCT04090424 about?
NCT04090424 is a clinical study titled "Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns". This is a multi-center, pivotal study to assess the safety and effectiveness of a new method of treating severe burns using NovoSorb® Biodegradable Temporizing Matrix (BTM).
What is the current status of trial NCT04090424?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2021-09-21. Estimated completion is 2026-12.
What conditions does trial NCT04090424 study?
This clinical trial studies the following conditions: Burns.
What interventions are being tested in trial NCT04090424?
The interventions under investigation include: Standard of Care (PROCEDURE), NovoSorb BTM (DEVICE).
Who is sponsoring clinical trial NCT04090424?
This trial is sponsored by PolyNovo Biomaterials Pty, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04090424 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Burns
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04090424's enrollment target sits among peer trials
150 7th of 36 higher than 30 of 36 other Burns trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Burns trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Suprathel® Use During Prolonged Field Care to Promote Healing and Reduce the Need for Grafting of Burn Wounds
RECRUITING · NA
-
Impact of a Telerehabilitation Program With Technology Enhancement on Post-burn Recovery
RECRUITING · NA
-
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation
ACTIVE NOT RECRUITING · NA
-
Virtual Reality in Burn Pain Management
COMPLETED · NA
-
Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar
COMPLETED · NA
-
VR for Pain Management During Adult Burn Dressing Change
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00412594 · 150 participants · Phase 2
Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia
- NCT01484730 · 150 participants
A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion
- NCT01985919 · 150 participants
Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples
- NCT02016248 · 150 participants · NA
SBRT Boost for Unfavorable Prostate Cancer'
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI