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NCT06596434 · ClinicalTrials.gov registry record · Phase 2
4-Aminopyridine to Treat Skin Burns
A Phase 2 study of Burns and Wounds and Injuries, sponsored by John Elfar.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT06596434: Recruiting Phase 2 study of Burns and Wounds and Injuries, sponsored by John Elfar.
NCT06596434 is a Phase 2 study of Burns and Wounds and Injuries that is actively recruiting participants, run by John Elfar. The registered enrollment target is 200 participants, above the 78-participant average among 36 other Burns trials with a reported enrollment target (156% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06596434, a Phase 2 study of Burns and Wounds and Injuries, is actively recruiting participants, sponsored by John Elfar.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin. There is a need to develop treatments to accelerate and improve healing of burn injuries. More research is needed to evaluate the role of 4-AP, a promising new agent with an excellent safety profile, on wound and burn healing. The investigational treatment will be used to test the hypothesis that 4-AP accelerates burn healing in traumatically burned patients.
Primary Outcome
Each subject will undergo detailed fiducial-marking augmented macroscopic imaging to determine baseline burn area measurement. These measurements will be repeated at each follow up study visit to assess healing rate.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Drug: 4-Aminopyridine
Study Locations (1)
Arizona
- University of Arizona - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2026-01-01 |
| Est. Completion | 2028-09 |
| Phase | Phase 2 |
What NCT06596434 shows while recruiting
NCT06596434 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 78-participant average among 36 other Burns trials with a reported enrollment target (156% higher).
The record links to 3 conditions, with Burns appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06596434 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT06596434 about?
NCT06596434 is a clinical study titled "4-Aminopyridine to Treat Skin Burns". Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin. There is a need to develop treatments to accelerate and improve healing of burn injuries. More research is needed to evaluate the role of...
What is the current status of trial NCT06596434?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2026-01-01. Estimated completion is 2028-09.
What conditions does trial NCT06596434 study?
This clinical trial studies the following conditions: Burns, Wounds and Injuries, Second Degree Burn.
What interventions are being tested in trial NCT06596434?
The interventions under investigation include: Placebo (OTHER), Drug: 4-Aminopyridine (DRUG).
Who is sponsoring clinical trial NCT06596434?
This trial is sponsored by John Elfar, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06596434 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Burns
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06596434's enrollment target sits among peer trials
200 5th of 36 higher than 32 of 36 other Burns trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Burns trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
RECRUITING · Phase 2
-
Cranial Electrotherapy Stimulation in Burned Patients
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VR for Burn Dressing Changes at Home
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Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
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Suprathel® Use During Prolonged Field Care to Promote Healing and Reduce the Need for Grafting of Burn Wounds
RECRUITING · NA
-
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
RECRUITING · Phase 4
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