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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Brain Diseases: early-phase trial registry

5 of 13 indexed Brain Diseases trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 5 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Brain Diseases: 13 US clinical trials tracked, 5 recruiting.

Brain Diseases is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 2 of these trials.

Enrollment posture brief

Registry condition brain-diseases

OPEN 5 | RECR 38% | LATE 1 | EARLY 3 | RANK #1315 | SPON 2

Nearest open-share peer: Anaplastic Oligodendroglioma (38% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Brain Diseases (this)38%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Brain Diseases

Brain Diseases lists 5 open slots (38% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Brain Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Brain Diseases is recruiting below its size-band peers.

    5 of 13 indexed trials (38.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Brain Diseases research.

    Washington University School of Medicine accounts for 2 of 13 trials (15.4%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Most Brain Diseases trials plan to enrol fewer than 100 people.

    Median target enrolment is 90 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Brain Diseases research is mostly interventional.

    11 interventional and 2 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 21Phase 31

Open and recent trials

13 total, page 1 of 1

RECRUITING 50,000 participants

University of Central Florida CereBank

University of Central Florida

NCT06876857

RECRUITING NA 120 participants

Metabolic and Hemodynamic Reserve in Pediatric SCA

Washington University School of Medicine

NCT04406818

RECRUITING NA 90 participants

Amygdala Memory Enhancement

Washington University School of Medicine

NCT05065450

RECRUITING Phase 1 73 participants

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Stemline Therapeutics

NCT05386108

RECRUITING NA 60 participants

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Jorge Gonzalez-Martinez

NCT07056361

ACTIVE NOT RECRUITING NA 20,000 participants

Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)

Sage Bionetworks

NCT02696603

ACTIVE NOT RECRUITING Phase 3 1,175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Eli Lilly and Company

NCT05738486

COMPLETED NA 340 participants

pRESET for Occlusive Stroke Treatment

phenox

NCT03994822

COMPLETED Phase 2 95 participants

A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)

Eli Lilly and Company

NCT04640077

COMPLETED 84 participants

Analysis of Brain Tumors Using Matrix Assisted Laser Desorption/Ionization Mass Spectrometry

Vanderbilt University Medical Center

NCT00592709

COMPLETED Phase 1 80 participants

A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases

AbbVie (prior sponsor, Abbott)

NCT00649207

COMPLETED NA 80 participants

Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers

Elizabeth K Rhodus

NCT05202223

COMPLETED NA 23 participants

Effects of Sensory Flicker and Electrical Flicker Stimulation

Emory University

NCT04188834

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 3 1

Named interventions

Most-linked intervention names on Brain Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Harmony at HOME (H@H) Behavioral
1 trials
Blackrock CereStim Device
1 trials
Customized version of DAVID device Device
1 trials
donanemab Drug
1 trials
Whole Brain Radiation Therapy Radiation
1 trials
ABT-888 Drug
1 trials
Mechanical Thrombectomy using the Solitaire Revascularization Device Device
1 trials
Mechanical Thrombectomy using the pRESET Thrombectomy device Device
1 trials

US sites by state

Facility locations filed on Brain Diseases trials. A trial with sites in several states counts in each.

Florida 4 trials
California 4 trials
Pennsylvania 3 trials
Ohio 3 trials
Missouri 3 trials
Massachusetts 3 trials
Illinois 3 trials
Georgia 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Brain Diseases page

13 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Brain Diseases condition card totals 13 registered trials; most-linked intervention Harmony at HOME (H@H); top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.