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NCT05038553 · ClinicalTrials.gov registry record

Chronic Pain in Rheumatoid Arthritis

A clinical trial of Pain and Arthritis, Rheumatoid, sponsored by Northwestern University.

Recruiting
Registry status
125
Enrollment target
5
Study locations

NCT05038553: Recruiting study of Pain and Arthritis, Rheumatoid, sponsored by Northwestern University.

NCT05038553 is a study of Pain and Arthritis, Rheumatoid that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 125 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (59% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05038553, a study of Pain and Arthritis, Rheumatoid, is actively recruiting participants, sponsored by Northwestern University.

RECRUITING
Registry status
125 participants
Enrollment target
5
Study locations

Study Summary

The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been shown to be involved in chronic pain.

Primary Outcome

Minimum value 0, maximum value 31; higher scores indicate worse outcomes

Interventions

  • OTHER No intervention

Study Locations (5)

Colorado

  • University of Colorado - Denver

Illinois

  • Northwestern University - Chicago

Maryland

  • Johns Hopkins University - Baltimore

Michigan

  • University of Michigan - Ann Arbor

New York

  • Hospital for Special Surgery - New York

Trial Details

FieldValue
Enrollment Target 125 participants
Start Date 2021-10-12
Est. Completion 2026-04-30
Northwestern University

1,209 total trials

What NCT05038553 shows while recruiting

NCT05038553 is an observational study that tracks outcomes without assigning an intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap, below the 304-participant average among 374 other Pain trials with a reported enrollment target (59% lower).

The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 1 intervention - of which No intervention is the first listed.

NCT05038553 lists 5 locations in 5 states (Colorado, Illinois, Maryland).

Frequently Asked Questions

What is clinical trial NCT05038553 about?

NCT05038553 is a clinical study titled "Chronic Pain in Rheumatoid Arthritis". The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, ...

What is the current status of trial NCT05038553?

This trial is currently recruiting. The enrollment target is 125 participants. The study started on 2021-10-12. Estimated completion is 2026-04-30.

What conditions does trial NCT05038553 study?

This clinical trial studies the following conditions: Pain, Arthritis, Rheumatoid.

What interventions are being tested in trial NCT05038553?

The interventions under investigation include: No intervention (OTHER).

Who is sponsoring clinical trial NCT05038553?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05038553 being conducted?

This trial has 5 study locations across Colorado, Illinois, Maryland, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05038553's enrollment target sits among peer trials

125 130th of 374 higher than 243 of 374 other Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05038553, the US trial registry maintained by the National Library of Medicine. NCT05038553 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.