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2026 data Public-data reference. official source

Anatomic Stage IIIC Breast Cancer AJCC v8

Open-data reference.

27 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING 250 participants

Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors

University of Southern California

NCT07259304

RECRUITING Phase 1 132 participants

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Mayo Clinic

NCT05269381

RECRUITING Phase 2 60 participants

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

M.D. Anderson Cancer Center

NCT04090567

RECRUITING Early Phase 1 50 participants

Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT05417308

RECRUITING NA 40 participants

A Quality of Life Intervention for Young African American Breast Cancer Survivors in Treatment

University of Alabama at Birmingham

NCT05243056

RECRUITING NA 27 participants

Transcutaneous Electrical Nerve Stimulation in Chemotherapy Induced Peripheral Neuropathy in Patients With Stage I-III Early Stage Breast Cancer

Emory University

NCT05368428

RECRUITING Phase 1 18 participants

Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer

Emory University

NCT06324240

RECRUITING Phase 1 18 participants

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Jonsson Comprehensive Cancer Center

NCT05319873

RECRUITING NA 15 participants

Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

M.D. Anderson Cancer Center

NCT02918474

ACTIVE NOT RECRUITING 1,410 participants

Infertility Survey Among Reproductive Age Women With Gynecological and Breast Cancer

M.D. Anderson Cancer Center

NCT04678414

ACTIVE NOT RECRUITING 1,336 participants

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

SWOG Cancer Research Network

NCT03939481

ACTIVE NOT RECRUITING Phase 2 1,100 participants

Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer

M.D. Anderson Cancer Center

NCT01334021

ACTIVE NOT RECRUITING Phase 3 1,056 participants

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

Alliance for Clinical Trials in Oncology

NCT04457596

ACTIVE NOT RECRUITING NA 332 participants

A Text-based Intervention in Improving Adherence to Hormone Therapy in Patients With Stage I-III Hormone Receptor Positive Breast Cancer

Thomas Jefferson University

NCT04086875

ACTIVE NOT RECRUITING Phase 2 249 participants

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

ECOG-ACRIN Cancer Research Group

NCT04001829

ACTIVE NOT RECRUITING NA 95 participants

Identifying Decision Making Needs for Older Adult Women With Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy

M.D. Anderson Cancer Center

NCT05049746

ACTIVE NOT RECRUITING NA 61 participants

Intensity Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Treating Patients With Lymph-Node Positive Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT03786354

ACTIVE NOT RECRUITING Phase 2 36 participants

Pembrolizumab in Treating Patients With Hormone Receptor Positive, Localized Inflammatory Breast Cancer Who Are Receiving Hormone Therapy and Did Not Achieve a Pathological Complete Response to Chemotherapy

M.D. Anderson Cancer Center

NCT02971748

ACTIVE NOT RECRUITING Phase 2 33 participants

STEMVAC in Patients With Early Stage Triple Negative Breast Cancer

University of Washington

NCT05455658

ACTIVE NOT RECRUITING NA 30 participants

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT05025059

ACTIVE NOT RECRUITING Phase 1 23 participants

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT03218826

COMPLETED NA 452 participants

Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT00507923

COMPLETED NA 23 participants

Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT03505671

COMPLETED Phase 1 20 participants

M7824 in Treating Patients With Stage II-III HER2 Positive Breast Cancer

M.D. Anderson Cancer Center

NCT03620201

COMPLETED Phase 1 18 participants

Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer

M.D. Anderson Cancer Center

NCT03207529

COMPLETED Phase 1 15 participants

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

M.D. Anderson Cancer Center

NCT03774472

COMPLETED Phase 1 11 participants

Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT04205903

Phase Distribution

PhaseTrial count
Early Phase 1 9
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anatomic Stage IIIC Breast Cancer AJCC v8 Trial Landscape

ClinicalTrials.gov lists 27 US studies indexed under Anatomic Stage IIIC Breast Cancer AJCC v8, and 9 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Anatomic Stage IIIC Breast Cancer AJCC v8 shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 14 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Anatomic Stage IIIC Breast Cancer AJCC v8 is led by M.D. Anderson Cancer Center with 11 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anatomic Stage IIIC Breast Cancer AJCC v8?

PlainTrial tracks 27 US clinical trials for Anatomic Stage IIIC Breast Cancer AJCC v8, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anatomic Stage IIIC Breast Cancer AJCC v8?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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