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ClinicalTrials.gov 6 recruiting now later-stage tilt small index

Age-related Cognitive Decline: later-stage trial registry

6 of 11 indexed Age-related Cognitive Decline trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,577 of 28,707 conditions by registered trial count.

11 US clinical trials · 6 currently recruiting · #1,577 of 28,707 conditions by registered trial count

Age-related Cognitive Decline: 11 US clinical trials tracked, 6 recruiting.

Age-related Cognitive Decline is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Posit Science Corporation, running 2 of these trials.

Enrollment posture brief

Registry condition age-related-cognitive-decline

OPEN 6 | RECR 55% | LATE 2 | EARLY 1 | RANK #1577 | SPON 2

Nearest open-share peer: Advanced Ovarian Carcinoma (55% recruiting · 11 trials)

Acute Pancreatitis81.8%Age-related Cognitive De (th…55%Acute Stroke45.5%Acquired Brain Injury36.4%Acute Lung Injury9.1%
Open-enrollment share among volume-matched conditions near Age-related Cognitive Decline

Age-related Cognitive Decline lists 6 open slots (55% of 11 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Age-related Cognitive Decline on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Age-related Cognitive Decline is recruiting above its size-band peers.

    6 of 11 indexed trials (54.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Age-related Cognitive Decline research.

    Posit Science Corporation accounts for 2 of 11 trials (18.2%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Age-related Cognitive Decline enrolment sits around 129 participants.

    Median target enrolment is 129 among the 11 trials that report a genuine target (sentinel values excluded). 5 of those (45.5%) plan for fewer than 100 participants.

  4. Age-related Cognitive Decline research is mostly interventional.

    10 interventional and 1 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 31Phase 41

Open and recent trials

11 total, page 1 of 1

RECRUITING Phase 3 7,600 participants

Preventing Alzheimer's With Cognitive Training

University of South Florida

NCT03848312

RECRUITING 1,700 participants

Older Breast Cancer Patients: Risk for Cognitive Decline

Georgetown University

NCT03451383

RECRUITING NA 1,305 participants

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

University of Alabama at Birmingham

NCT04171323

RECRUITING NA 240 participants

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

University of Southern California

NCT06410157

RECRUITING Phase 1 60 participants

Acute Effects of THC in Older Adult

Yale University

NCT06948136

RECRUITING NA 20 participants

Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment

The University of Texas Medical Branch, Galveston

NCT07416799

COMPLETED NA 135 participants

Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB

Posit Science Corporation

NCT05599490

COMPLETED Phase 4 129 participants

Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training

Washington University School of Medicine

NCT03272711

COMPLETED NA 83 participants

Attention Training for Learning Enhancement and Resilience Trial

Posit Science Corporation

NCT02416401

COMPLETED NA 37 participants

Effects of Tart Cherry Juice on the Body

University of Delaware

NCT02922920

COMPLETED NA 24 participants

Cognitive Multi-Tasking Training in Healthy Older Adults

Columbia University

NCT04195230

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Age-related Cognitive Decline records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computerized Plasticity-Based Adaptive Cognitive Training Other
2 trials
Computerized Cognitive Stimulation Behavioral
2 trials
Cognitive Training Behavioral
2 trials
Commercially available computerized training Other
1 trials
Multi-tasking Training Behavioral
1 trials
Tart cherry juice Other
1 trials
Cognitive training program Behavioral
1 trials
Vortioxetine 10 mg Drug
1 trials

US sites by state

Facility locations filed on Age-related Cognitive Decline trials. A trial with sites in several states counts in each.

Texas 2 trials
South Carolina 2 trials
Iowa 2 trials
Florida 2 trials
California 2 trials
New York 1 trials
North Carolina 1 trials
Missouri 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Age-related Cognitive Decline page

11 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 6 Age-related Cognitive Decline trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Posit Science Corporation sponsors the most Age-related Cognitive Decline trials on record, review their full trial history before evaluating a specific study. See Posit Science Corporation's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Age-related Cognitive Decline condition card totals 11 registered trials; most-linked intervention Computerized Plasticity-Based Adaptive Cognitive Training; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.