Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Age-related Cognitive Decline
Open-data reference.
10 US clinical trials · 6 currently recruiting
Active & Recent Trials
Preventing Alzheimer's With Cognitive Training
University of South Florida
NCT03848312
Older Breast Cancer Patients: Risk for Cognitive Decline
Georgetown University
NCT03451383
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
University of Alabama at Birmingham
NCT04171323
Cardiac-Control Affecting Learning Through Mindfulness (CALM)
University of Southern California
NCT06410157
Acute Effects of THC in Older Adult
Yale University
NCT06948136
Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment
The University of Texas Medical Branch, Galveston
NCT07416799
Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB
Posit Science Corporation
NCT05599490
Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training
Washington University School of Medicine
NCT03272711
Attention Training for Learning Enhancement and Resilience Trial
Posit Science Corporation
NCT02416401
Cognitive Multi-Tasking Training in Healthy Older Adults
Columbia University
NCT04195230
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Age-related Cognitive Decline Trial Landscape
ClinicalTrials.gov lists 10 US studies indexed under Age-related Cognitive Decline, and 6 of those are currently open to recruitment — roughly 60% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Age-related Cognitive Decline shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Age-related Cognitive Decline is led by Posit Science Corporation with 2 indexed trials, alongside 8 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Age-related Cognitive Decline?
PlainTrial tracks 10 US clinical trials for Age-related Cognitive Decline, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Age-related Cognitive Decline?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.