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ClinicalTrials.gov 6 recruiting now official registry

Age-related Cognitive Decline clinical trials

6 of 11 indexed Age-related Cognitive Decline trials are currently recruiting.

11 US clinical trials · 6 currently recruiting

Age-related Cognitive Decline is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Posit Science Corporation, running 2 of these trials.

The research picture

Age-related Cognitive Decline has 11 registered US clinical trials, 6 of them open to new participants right now, about 55% of the total.

6
recruiting participants now
55%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Posit Science Corporation
Phase 11Phase 31Phase 41

Active & Recent Trials

11 total, page 1 of 1

RECRUITING Phase 3 7,600 participants

Preventing Alzheimer's With Cognitive Training

University of South Florida

NCT03848312

RECRUITING 1,700 participants

Older Breast Cancer Patients: Risk for Cognitive Decline

Georgetown University

NCT03451383

RECRUITING NA 1,305 participants

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

University of Alabama at Birmingham

NCT04171323

RECRUITING NA 240 participants

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

University of Southern California

NCT06410157

RECRUITING Phase 1 60 participants

Acute Effects of THC in Older Adult

Yale University

NCT06948136

RECRUITING NA 20 participants

Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment

The University of Texas Medical Branch, Galveston

NCT07416799

COMPLETED NA 135 participants

Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB

Posit Science Corporation

NCT05599490

COMPLETED Phase 4 129 participants

Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training

Washington University School of Medicine

NCT03272711

COMPLETED NA 83 participants

Attention Training for Learning Enhancement and Resilience Trial

Posit Science Corporation

NCT02416401

COMPLETED NA 37 participants

Effects of Tart Cherry Juice on the Body

University of Delaware

NCT02922920

COMPLETED NA 24 participants

Cognitive Multi-Tasking Training in Healthy Older Adults

Columbia University

NCT04195230

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Age-related Cognitive Decline Trial Landscape

11 indexed Age-related Cognitive Decline studies · 6 recruiting (55%).

Phase mix: 2 late (III/IV) vs 1 early (I/II).

Top sponsor: Posit Science Corporation (2 trials), 9 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Age-related Cognitive Decline?

PlainTrial tracks 11 US clinical trials for Age-related Cognitive Decline, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Age-related Cognitive Decline?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.