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NCT01898715 · ClinicalTrials.gov registry record · Phase 1
Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma
A Phase 1 study of Adrenocortical Carcinoma and ACC, sponsored by Millendo Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 63
- Enrollment target
- 5
- Study locations
NCT01898715 is a Phase 1 study of Adrenocortical Carcinoma and ACC that has completed, run by Millendo Therapeutics. The registered enrollment target is 63 participants, below the 356-participant average among 8 other Adrenocortical Carcinoma trials with a reported enrollment target (82% lower). The trial reports 5 study locations across 5 states.
The verdict
NCT01898715, a Phase 1 study of Adrenocortical Carcinoma and ACC, has completed, sponsored by Millendo Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 63 participants
- Enrollment target
- 5
- Study locations
Study Summary
This first-in-human study is designed to establish the safety and tolerability of ATR-101 in patients with advanced adrenocortical carcinoma whose tumor has progressed on standard therapy. Information will also be collected to determine how long ATR-101 stays in the blood, and if any effect on tumor progression is seen. Biomarkers (blood and urine tests) will determine if any effects on production of steroid hormones (cortisol, aldosterone, estrogen and testosterone) are seen.
Conditions Studied
Interventions
- DRUG ATR-101
Study Locations (5)
Florida
- Moffitt Cancer Center - Tampa
Maryland
- National Institutes of Health/National Cancer Institute - Bethesda
Michigan
- University of Michigan Cancer Center - Ann Arbor
Texas
- MDAnderson Cancer Center - Houston
Other
- Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg - Würzburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 63 participants |
| Start Date | 2013-08-13 |
| Est. Completion | 2017-10-17 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01898715
The ClinicalTrials.gov registry entry for NCT01898715 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 356-participant average among 8 other Adrenocortical Carcinoma trials with a reported enrollment target (82% lower). The listed sponsor is Millendo Therapeutics, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Adrenocortical Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which ATR-101 is the first listed.
NCT01898715 reports 5 study locations spanning 5 distinct geographic areas - top geographies include Florida, Maryland, Michigan.
Frequently Asked Questions
What is clinical trial NCT01898715 about?
NCT01898715 is a clinical study titled "Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma". This first-in-human study is designed to establish the safety and tolerability of ATR-101 in patients with advanced adrenocortical carcinoma whose tumor has progressed on standard therapy. Information will also be collected to determine how long ATR-101 stays in the blood, and if any effect on tumor...
What is the current status of trial NCT01898715?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 63 participants. The study started on 2013-08-13. Estimated completion is 2017-10-17.
What conditions does trial NCT01898715 study?
This clinical trial studies the following conditions: Adrenocortical Carcinoma, ACC, Adrenal Cancer.
What interventions are being tested in trial NCT01898715?
The interventions under investigation include: ATR-101 (DRUG).
Who is sponsoring clinical trial NCT01898715?
This trial is sponsored by Millendo Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01898715 being conducted?
This trial has 5 study locations across Florida, Maryland, Michigan, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.