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ClinicalTrials.gov 12 recruiting now early-phase tilt small index

Atrial Fibrillation (AF): early-phase trial registry

12 of 18 indexed Atrial Fibrillation (AF) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #953 of 28,707 conditions by registered trial count.

18 US clinical trials · 12 currently recruiting · #953 of 28,707 conditions by registered trial count

Atrial Fibrillation (AF): 18 US clinical trials tracked, 12 recruiting.

Atrial Fibrillation (AF) is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 3 of these trials.

Enrollment posture brief

Registry condition atrial-fibrillation-af

OPEN 12 | RECR 67% | LATE 1 | EARLY 2 | RANK #953 | SPON 3

Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)

Atrial Fibrillation (this)67%Arrhythmias, Cardiac27.8%Androgenetic Alopecia16.7%Anemia, Sickle Cell16.7%Acquired Immunodeficiency Sy5.6%
Open-enrollment share among volume-matched conditions near Atrial Fibrillation (AF)

Atrial Fibrillation (AF) lists 12 open slots (67% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Atrial Fibrillation (AF) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Atrial Fibrillation (AF) is recruiting above its size-band peers.

    12 of 18 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Atrial Fibrillation (AF) research.

    University of California, San Francisco accounts for 3 of 18 trials (16.7%). 13 distinct sponsors appear on at least one study for this condition label.

  3. Typical Atrial Fibrillation (AF) enrolment sits around 458 participants.

    Median target enrolment is 458 among the 18 trials that report a genuine target (sentinel values excluded). 0 of those (0%) plan for fewer than 100 participants.

  4. Atrial Fibrillation (AF) research is mostly interventional.

    13 interventional and 5 observational studies make up this index (72.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22Phase 31

Open and recent trials

18 total, page 1 of 1

RECRUITING Phase 3 1,900 participants

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Anthos Therapeutics

NCT05712200

RECRUITING 1,780 participants

Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)

McMaster University

NCT06844227

RECRUITING Phase 2 1,200 participants

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Regeneron Pharmaceuticals

NCT07175428

RECRUITING NA 1,000 participants

Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity

University of California, San Francisco

NCT06995391

RECRUITING 1,000 participants

Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.

Cardiovascular Innovation and Research Institute

NCT03428048

RECRUITING NA 920 participants

Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

McMaster University

NCT06957366

RECRUITING NA 699 participants

A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

Boston Scientific Corporation

NCT07187115

RECRUITING NA 423 participants

Artificial Intelligence Mapping and Ablation of Non-Pulmonary Vein Electrical Drivers of AF Study

Vektor Medical

NCT06935591

RECRUITING NA 360 participants

Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Arga Medtech

NCT06784466

RECRUITING 100 participants

Incidence of Long-TeRm Atrial Fibrillation After Acute Illness

University of California, San Diego

NCT07434674

RECRUITING NA 100 participants

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

University of California, San Francisco

NCT07220525

RECRUITING NA 100 participants

Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation

University of California, San Francisco

NCT06754176

ACTIVE NOT RECRUITING Phase 2 1,287 participants

Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation

Anthos Therapeutics

NCT04755283

ACTIVE NOT RECRUITING NA 458 participants

Abbott Medical - VERITAS Study

Abbott Medical Devices

NCT06707688

ACTIVE NOT RECRUITING 336 participants

Phase-Aligned Atrial Fibrillation Mapping

Larisa Tereshchenko, MD, PhD

NCT06892561

ACTIVE NOT RECRUITING 232 participants

Detection and Classification of Cardiac Rhythm and Atrial Fibrillation Using a Finger-worn Ring

Everbeat

NCT06892938

ACTIVE NOT RECRUITING NA 188 participants

A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

Abbott Medical Devices

NCT06676072

ACTIVE NOT RECRUITING NA 150 participants

AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment

AtriCure

NCT03732794

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on Atrial Fibrillation (AF) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Abelacimab Biological
2 trials
PFA Ablation catheter Device
1 trials
Amulet™ 2 Left Atrial Appendage (LAA) Occluder Device
1 trials
AtriCure CryoICE & AtriClip LAA Exclusion Device
1 trials
Atrial Fibrillation Identification Diagnostic test
1 trials
Argá Medtech Coherent Sine-Burst Electroporation (CSE) Ablation System Device
1 trials
Rivaroxaban Drug
1 trials
FARAPULSE Pulsed Field Ablation (PFA) System and Opal HDx Mapping System Device
1 trials

US sites by state

Facility locations filed on Atrial Fibrillation (AF) trials. A trial with sites in several states counts in each.

California 11 trials
New York 8 trials
Michigan 8 trials
Georgia 7 trials
Illinois 6 trials
Florida 6 trials
Ohio 5 trials
Arizona 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Atrial Fibrillation (AF) page

18 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Atrial Fibrillation (AF) condition card totals 18 registered trials; most-linked intervention Abelacimab; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.