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NCT06746623 · ClinicalTrials.gov registry record · NA
Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux
A NA study of Tobacco Use and Barrett Esophagus, sponsored by Louis Stokes VA Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 1
- Study location
NCT06746623 is a NA study of Tobacco Use and Barrett Esophagus that is actively recruiting participants, run by Louis Stokes VA Medical Center. The registered enrollment target is 400 participants, roughly in line with the 374-participant average among 76 other Tobacco Use trials with a reported enrollment target. The trial reports 1 study location across 1 state.
The verdict
NCT06746623, a NA study of Tobacco Use and Barrett Esophagus, is actively recruiting participants, sponsored by Louis Stokes VA Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
The veteran population is at increased risk for EAC and its precursor lesion, Barrett's esophagus (BE), due to increased prevalence of disease risk factors compared to the general population. BE is traditionally diagnosed only when patients undergo endoscopy with biopsies. However, due to the high cost of endoscopy and the lack of studies proving efficacy of screening, endoscopy to screen for BE is not routinely recommended. A simpler screening procedure similar to a pap smear would be an ideal way to sample the esophageal tissue for cancer and its precursor condition, BE. This study proposes a non-endoscopic detection method administered in outpatient offices which would increase subsequent endoscopic detection of BE. The study team will be enrolling veterans who do not have history of gastroesophageal reflux but have multiple risk factors for esophageal adenocarcinoma.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Enrolled participants will complete Esocheck/Esoguard and diagnostic upper endoscopy.
Study Locations (1)
Ohio
- VA Northeast Ohio Healthcare System - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2025-04-11 |
| Est. Completion | 2028-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06746623
The ClinicalTrials.gov registry entry for NCT06746623 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 374-participant average among 76 other Tobacco Use trials with a reported enrollment target. The listed sponsor is Louis Stokes VA Medical Center, which has 10 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Tobacco Use appearing as the primary indexed condition, and to 1 intervention - of which Enrolled participants will complete Esocheck/Esoguard and diagnostic upper endoscopy. is the first listed.
NCT06746623 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT06746623 about?
NCT06746623 is a clinical study titled "Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux". The veteran population is at increased risk for EAC and its precursor lesion, Barrett's esophagus (BE), due to increased prevalence of disease risk factors compared to the general population. BE is traditionally diagnosed only when patients undergo endoscopy with biopsies. However, due to the high c...
What is the current status of trial NCT06746623?
This trial is currently recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2025-04-11. Estimated completion is 2028-12-31.
What conditions does trial NCT06746623 study?
This clinical trial studies the following conditions: Tobacco Use, Barrett Esophagus, Veterans, Obese Patients, Family History of Esophageal Cancer.
What interventions are being tested in trial NCT06746623?
The interventions under investigation include: Enrolled participants will complete Esocheck/Esoguard and diagnostic upper endoscopy. (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06746623?
This trial is sponsored by Louis Stokes VA Medical Center, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06746623 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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