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NCT04903028 · ClinicalTrials.gov registry record · NA

RTMS Targets Neural Circuits for Smoking Cessation

A NA study of Tobacco Use and Cigarette Smoking, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
64
Enrollment target
2
Study locations

NCT04903028: Recruiting NA study of Tobacco Use and Cigarette Smoking, sponsored by Medical University of South Carolina.

NCT04903028 is a NA study of Tobacco Use and Cigarette Smoking that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 64 participants, below the 378-participant average among 76 other Tobacco Use trials with a reported enrollment target (83% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04903028, a NA study of Tobacco Use and Cigarette Smoking, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
64 participants
Enrollment target
2
Study locations

Study Summary

Cigarette smoking is a significant public health concern. Transcranial magnetic stimulation (TMS) is a non-invasive form of brain stimulation that has already displayed remarkable potential for producing novel, non-pharmacological interventions for depression and cigarette smokers. In this study, investigators will use brain MRI to guide TMS therapy for smoking cessation.

Primary Outcome

Measured by self-report of smoking abstinence in the past 4 weeks and confirmed using urine cotinine measurement.

Interventions

  • DEVICE Sham rTMS
  • DEVICE Active rTMS 10 Hz DLPFC

Study Locations (2)

South Carolina

  • Medical University of South Carolina - Charleston
  • Medical University of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 64 participants
Start Date 2021-05-15
Est. Completion 2027-04-04
Phase NA

What NCT04903028 shows while recruiting

NCT04903028 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 378-participant average among 76 other Tobacco Use trials with a reported enrollment target (83% lower).

The record links to 2 conditions, with Tobacco Use appearing as the primary indexed condition, and to 2 interventions - of which Sham rTMS is the first listed.

NCT04903028 reports a single indexed study location in South Carolina.

Frequently Asked Questions

What is clinical trial NCT04903028 about?

NCT04903028 is a clinical study titled "RTMS Targets Neural Circuits for Smoking Cessation". Cigarette smoking is a significant public health concern. Transcranial magnetic stimulation (TMS) is a non-invasive form of brain stimulation that has already displayed remarkable potential for producing novel, non-pharmacological interventions for depression and cigarette smokers. In this study, in...

What is the current status of trial NCT04903028?

This trial is currently recruiting. It is a NA study. The enrollment target is 64 participants. The study started on 2021-05-15. Estimated completion is 2027-04-04.

What conditions does trial NCT04903028 study?

This clinical trial studies the following conditions: Tobacco Use, Cigarette Smoking.

What interventions are being tested in trial NCT04903028?

The interventions under investigation include: Sham rTMS (DEVICE), Active rTMS 10 Hz DLPFC (DEVICE).

Who is sponsoring clinical trial NCT04903028?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04903028 being conducted?

This trial has 2 study locations across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Tobacco Use

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04903028's enrollment target sits among peer trials

64 47th of 76 higher than 29 of 76 other Tobacco Use trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Tobacco Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04903028, the US trial registry maintained by the National Library of Medicine. NCT04903028 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.