Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07108166 · ClinicalTrials.gov registry record · NA
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
A NA study of Smoking and COPD, sponsored by Philip Morris Products S.A..
- Recruiting
- Registry status
- NA
- Development phase
- 290
- Enrollment target
- 20
- Study locations
NCT07108166: Recruiting NA study of Smoking and COPD, sponsored by Philip Morris Products S.A..
NCT07108166 is a NA study of Smoking and COPD that is actively recruiting participants, run by Philip Morris Products S.A.. The registered enrollment target is 290 participants, below the 453-participant average among 123 other Smoking trials with a reported enrollment target (36% lower). The trial reports 20 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07108166, a NA study of Smoking and COPD, is actively recruiting participants, sponsored by Philip Morris Products S.A..
- RECRUITING
- Registry status
- NA
- Development phase
- 290 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this randomized study is to demonstrate direct clinical benefit, i.e., observed benefits in how humans with COPD feel in terms of symptoms (e.g., cough frequency, shortness of breath, and other respiratory symptoms) and function (e.g., lung function, and six-minute walking test \[6MWT\]) after switching to THS compared to continuing to smoking cigarettes.
Primary Outcome
To demonstrate a change in 24-hour cough frequency in COPD patients with chronic bronchitis switching from cigarette (CIG) to THS compared to those who continue to smoke CIG.
Conditions Studied
Interventions
- OTHER Cigarette
- OTHER THS
Study Locations (20)
Florida
- Clinical Research of West Florida, Inc. - Clearwater
- Florida International Medical Research - Coral Gables
- Alfa Medical Research - Davie
- Omega Research Debary, LLC - DeBary
- D&H Doral Research Center - Doral
- Felicidad Med Research - Hialeah
- The Medici Medical Research, LLC - Hollywood
- D&H Pompano Research Center - Margate
- Med-Care Research Corp - Miami
- EMDA Clincal Research - Miami
- Sones Medical Research - Miami
- Suncoast Research Group, LLC dba Flourish Research - Miami
- Melgar-Caro Medcenter and Community Research - Miami
- D&H National Research Center- Miami - Miami
- Biomed Research & Medical Center.Llc - Miami
- Global Health Clinical Trials Corp. - Miami
- Professional Research Center Inc - Miami
- Newgen Health Group - Miami
- Reserka LLC - Miami
- Pharma Medical Innovations - Miami Lakes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 290 participants |
| Start Date | 2025-04-02 |
| Est. Completion | 2026-11 |
| Phase | NA |
What NCT07108166 shows while recruiting
NCT07108166 is an interventional study that assigns participants to a tested intervention. The registered 290 participants enrollment target is mid-sized for trials with a published cap, below the 453-participant average among 123 other Smoking trials with a reported enrollment target (36% lower).
The record links to 3 conditions, with Smoking appearing as the primary indexed condition, and to 2 interventions - of which Cigarette is the first listed.
NCT07108166 names 20 study sites across 1 states, led by Florida.
Frequently Asked Questions
What is clinical trial NCT07108166 about?
NCT07108166 is a clinical study titled "Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS". The purpose of this randomized study is to demonstrate direct clinical benefit, i.e., observed benefits in how humans with COPD feel in terms of symptoms (e.g., cough frequency, shortness of breath, and other respiratory symptoms) and function (e.g., lung function, and six-minute walking test \[6MWT...
What is the current status of trial NCT07108166?
This trial is currently recruiting. It is a NA study. The enrollment target is 290 participants. The study started on 2025-04-02. Estimated completion is 2026-11.
What conditions does trial NCT07108166 study?
This clinical trial studies the following conditions: Smoking, COPD, Tobacco Use.
What interventions are being tested in trial NCT07108166?
The interventions under investigation include: Cigarette (OTHER), THS (OTHER).
Who is sponsoring clinical trial NCT07108166?
This trial is sponsored by Philip Morris Products S.A., which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07108166 being conducted?
This trial has 20 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07108166's enrollment target sits among peer trials
290 44th of 123 higher than 80 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Clinical Alternatives for Reducing Harm Using E-cigarettes
RECRUITING · NA
-
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
RECRUITING · NA
-
Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network
RECRUITING · NA
-
Enhancing Motivation to Quit Smoking Via Self-Help Intervention Targeted to Cancer Type
RECRUITING · NA
-
Personalized Tobacco Treatment in Primary Care (MOTIVATE)
RECRUITING · NA
-
Take A Break - Rural
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00775476 · 290 participants · Phase 2
Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine
- NCT01874197 · 290 participants · NA
Branched Thoracic Endovascular Grafts for the Treatment of Thoraco-abdominal Aortic
- NCT04331353 · 290 participants · NA
The Allergen Reduction and Child Health Study (ARCHS)
- NCT04649008 · 290 participants · Early Phase 1
Localizing Epileptic Networks Using MRI and iEEG
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI