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NCT03257033 · ClinicalTrials.gov registry record · Phase 3

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

A Phase 3 study of Locally Advanced Pancreatic Cancer, sponsored by RenovoRx.

Recruiting
Registry status
Phase 3
Development phase
190
Enrollment target
20
Study locations

NCT03257033 is a Phase 3 study of Locally Advanced Pancreatic Cancer that is actively recruiting participants, run by RenovoRx. The registered enrollment target is 190 participants, above the 58-participant average among 3 other Locally Advanced Pancreatic Cancer trials with a reported enrollment target (228% higher). The trial reports 20 study locations across 11 states.

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The verdict

NCT03257033, a Phase 3 study of Locally Advanced Pancreatic Cancer, is actively recruiting participants, sponsored by RenovoRx.

RECRUITING
Registry status
Phase 3
Development phase
190 participants
Enrollment target
20
Study locations

Study Summary

The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.

Interventions

  • DRUG Gemcitabine
  • DRUG nab-paclitaxel
  • DEVICE RenovoCath

Study Locations (20)

Florida

  • 21st Century Oncology - Fort Myers
  • Miami Cancer Center - Miami
  • Sarasota Memorial Health Care System - Sarasota
  • Moffitt Cancer Center - Tampa
  • ASCLEPES Research Centers - Weeki Wachee

California

  • VA Loma Linda Healthcare System - Loma Linda
  • Sutter Cancer Center Sacramento - Sacramento

Colorado

  • Rocky Mountain Cancer Centers - Denver
  • Comprehensive Cancer Care and Research Institute of Colorado, CCCRIC - Englewood

District of Columbia

  • Sibley Memorial Hospital - a member of Johns Hopkins medicine - Washington D.C.
  • Georgetown University - Washington D.C.

Louisiana

  • Ochsner Clinic Foundation - New Orleans
  • LSU Health Shreveport - Shreveport

New Jersey

  • MD Anderson Cancer Center at Cooper Hospital - Camden
  • Atlantic Health System - Morristown Medical Center - Morristown

Georgia

  • Piedmont-Columbus Regional - John B. Amos Cancer Center - Columbus

Iowa

  • University of Iowa Hospitals and Clinics - Holden Comprehensive Cancer Center - Iowa City

Trial Details

FieldValue
Enrollment Target 190 participants
Start Date 2018-03-12
Est. Completion 2026-09
Phase Phase 3

Sponsor

RenovoRx

4 total trials

What the Registry Record Tells You About NCT03257033

The ClinicalTrials.gov registry entry for NCT03257033 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 190 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 58-participant average among 3 other Locally Advanced Pancreatic Cancer trials with a reported enrollment target (228% higher). The listed sponsor is RenovoRx, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Locally Advanced Pancreatic Cancer appearing as the primary indexed condition, and to 3 interventions - of which Gemcitabine is the first listed.

NCT03257033 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Florida, California, Colorado.

Frequently Asked Questions

What is clinical trial NCT03257033 about?

NCT03257033 is a clinical study titled "Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC". The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.

What is the current status of trial NCT03257033?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 190 participants. The study started on 2018-03-12. Estimated completion is 2026-09.

What conditions does trial NCT03257033 study?

This clinical trial studies the following conditions: Locally Advanced Pancreatic Cancer.

What interventions are being tested in trial NCT03257033?

The interventions under investigation include: Gemcitabine (DRUG), nab-paclitaxel (DRUG), RenovoCath (DEVICE).

Who is sponsoring clinical trial NCT03257033?

This trial is sponsored by RenovoRx, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03257033 being conducted?

This trial has 20 study locations across California, Colorado, District of Columbia, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.