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2026 data Public-data reference. official source

Psychotic Disorders

Open-data reference.

23 US clinical trials · 6 currently recruiting

Active & Recent Trials

RECRUITING NA 2,500 participants

Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

Maastricht University Medical Center

NCT05656469

RECRUITING NA 480 participants

Racial Disparities in the Expression of Paranoia

Indiana University

NCT07460453

RECRUITING NA 192 participants

A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Massachusetts General Hospital

NCT06929442

RECRUITING NA 190 participants

CBT-CP for Veterans With SMI

VA Office of Research and Development

NCT06758414

RECRUITING NA 70 participants

Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

Massachusetts General Hospital

NCT05962879

RECRUITING NA 69 participants

A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness

VA Office of Research and Development

NCT05537376

ACTIVE NOT RECRUITING NA 220 participants

Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial

University of California, Los Angeles

NCT04338152

ACTIVE NOT RECRUITING NA 174 participants

Reconnecting to Ourselves and Others in Virtual Meetings (ROOM)

Massachusetts General Hospital

NCT06360562

ACTIVE NOT RECRUITING Phase 1 80 participants

Cannabinoids, Learning, and Memory

Yale University

NCT02407808

COMPLETED NA 292 participants

Early Detection and Intervention for the Prevention of Psychosis

MaineHealth

NCT00531518

COMPLETED Phase 1 281 participants

Relative Bioavailability of LY03010 Compared to Listed Drug

Luye Pharma Group

NCT04922593

COMPLETED 187 participants

Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis

Mclean Hospital

NCT01688765

COMPLETED Phase 4 180 participants

Antipsychotic Discontinuation in Alzheimer's Disease

New York State Psychiatric Institute

NCT00417482

COMPLETED Phase 2 168 participants

Supported Employment: Motivational Enhancement for Entry and Outcome

VA Office of Research and Development

NCT01041976

COMPLETED Phase 2 133 participants

Family-Focused Therapy for Youth With Early-Onset Bipolar or Psychotic Disorders

University of California, Los Angeles

NCT02097563

COMPLETED Phase 4 127 participants

Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics

Johns Hopkins University

NCT00806234

COMPLETED NA 100 participants

Psychosis: Early Detection, Intervention and Prevention

MaineHealth

NCT01597141

COMPLETED 73 participants

Clinical and Biological Characteristics of Psychotic Depression

Stanford University

NCT00576095

COMPLETED Phase 2 38 participants

Treating Smokers With Mental Illness

University of Minnesota

NCT03822416

COMPLETED NA 30 participants

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness

University Hospitals Cleveland Medical Center

NCT02085447

COMPLETED Early Phase 1 18 participants

Acceptance and Commitment Therapy for the Inpatient Treatment of Psychosis

VA Office of Research and Development

NCT01981356

COMPLETED NA 10 participants

Mobile After-Care Intervention to Support Post-Hospital Transition (MACS)

Butler Hospital

NCT03769493

COMPLETED NA 8 participants

Antidepressant and Antipsychotic to Treat Attenuated Positive and Negative Symptoms

Northwell Health

NCT00169988

Phase Distribution

PhaseTrial count
Early Phase 1 3
Phase 2 3
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Psychotic Disorders Trial Landscape

ClinicalTrials.gov lists 23 US studies indexed under Psychotic Disorders, and 6 of those are currently open to recruitment — roughly 26% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Psychotic Disorders shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Psychotic Disorders is led by VA Office of Research and Development with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Psychotic Disorders?

PlainTrial tracks 23 US clinical trials for Psychotic Disorders, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Psychotic Disorders?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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