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NCT06039709 · ClinicalTrials.gov registry record · Phase 1
Sonodynamic Therapy in Patients With Recurrent GBM
A Phase 1 study of Glioblastoma Multiforme and Recurrent Glioblastoma, sponsored by Shayan Moosa, MD.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
- 1
- Study location
NCT06039709 is a Phase 1 study of Glioblastoma Multiforme and Recurrent Glioblastoma that is actively recruiting participants, run by Shayan Moosa, MD. The registered enrollment target is 11 participants, below the 97-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06039709, a Phase 1 study of Glioblastoma Multiforme and Recurrent Glioblastoma, is actively recruiting participants, sponsored by Shayan Moosa, MD.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients diagnosed with glioblastoma (GBM) are faced with limited treatment options. This pilot study will evaluate the safety and feasibility of combining an investigational drug called 5-ALA with neuronavigation-guided low-intensity focused ultrasound (LIFU) for patients who have recurrent GBM. Focused ultrasound (FUS) can be used to non-invasively destroy tumor tissue while preserving normal tissue. When FUS is combined with 5-ALA, this combinatorial approach is called sonodynamic therapy (SDT), and this investigational therapy is being tested for its ability to cause damage to GBM cells. SDT will take place prior to surgery for recurrent GBM.
Conditions Studied
Interventions
- COMBINATION_PRODUCT 5-ALA and Low-Intensity Focused Ultrasound (SDT)
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2024-01-31 |
| Est. Completion | 2026-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06039709
The ClinicalTrials.gov registry entry for NCT06039709 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 97-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (89% lower). The listed sponsor is Shayan Moosa, MD, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Glioblastoma Multiforme appearing as the primary indexed condition, and to 1 intervention - of which 5-ALA and Low-Intensity Focused Ultrasound (SDT) is the first listed.
NCT06039709 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.
Frequently Asked Questions
What is clinical trial NCT06039709 about?
NCT06039709 is a clinical study titled "Sonodynamic Therapy in Patients With Recurrent GBM". Patients diagnosed with glioblastoma (GBM) are faced with limited treatment options. This pilot study will evaluate the safety and feasibility of combining an investigational drug called 5-ALA with neuronavigation-guided low-intensity focused ultrasound (LIFU) for patients who have recurrent GBM. Fo...
What is the current status of trial NCT06039709?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2024-01-31. Estimated completion is 2026-06.
What conditions does trial NCT06039709 study?
This clinical trial studies the following conditions: Glioblastoma Multiforme, Recurrent Glioblastoma, GBM.
What interventions are being tested in trial NCT06039709?
The interventions under investigation include: 5-ALA and Low-Intensity Focused Ultrasound (SDT) (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06039709?
This trial is sponsored by Shayan Moosa, MD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06039709 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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