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RECRUITING Phase 2

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

NCT07038876 · View on ClinicalTrials.gov ↗

Study Summary

ML-007C-MA-211 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered ML-007C-MA in inpatient adult participants aged 18 to 64 years with schizophrenia experiencing an acute exacerbation of psychosis. The primary objective is to evaluate the efficacy of ML-007C-MA compared with placebo in the treatment of subjects with inadequately controlled symptoms of schizophrenia as measured by the Positive and Negative Syndrome Scale (PANSS) Total Score.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG ML-007C-MA BID
  • DRUG ML-007C-MA QD

Study Locations (20)

California

  • Clinical Site — Bellflower
  • Clinical Site — Culver City
  • Clinical Site — Garden Grove
  • Clinical Site — Lemon Grove
  • Clinical Site — Los Angeles
  • Clinical Site — Montclair
  • Clinical Site — Orange
  • Clinical Site — Riverside
  • Clinical Site — San Diego
  • Clinical Site — Santee
  • Clinical Site — Sherman Oaks
  • Clinical Site — Torrance

Florida

  • Clinical Site — Hollywood
  • Clinical Site — Miami Lakes
  • Clinical Site — West Palm Beach

Georgia

  • Clinical Site — Atlanta
  • Clinical Site — Decatur

Arkansas

  • Clinical Site — Little Rock

Illinois

  • Clinical Site — Chicago

New Jersey

  • Clinical Site — Marlton

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2025-06-27
Est. Completion 2026-08
Phase Phase 2

Sponsor

MapLight Therapeutics

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07038876

The ClinicalTrials.gov registry entry for NCT07038876 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MapLight Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07038876 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07038876 about?

NCT07038876 is a clinical study titled "A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia". ML-007C-MA-211 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered ML-007C-MA in inpatient adult participants aged 18 to 64 years with schizophrenia experiencing an acute exacerbation of psychosis. The primary ob...

What is the current status of trial NCT07038876?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 2025-06-27. Estimated completion is 2026-08.

What conditions does trial NCT07038876 study?

This clinical trial studies the following conditions: Schizophrenia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07038876?

The interventions under investigation include: Placebo (DRUG), ML-007C-MA BID (DRUG), ML-007C-MA QD (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07038876?

This trial is sponsored by MapLight Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07038876 being conducted?

This trial has 20 study locations across Arkansas, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial