Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
NCT05611242 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke (AIS) from intracranial vessel occlusion (IVO) in the anterior circulation and have a proximal carotid occlusive disease (occlusion or severe stenosis).
Conditions Studied
Interventions
- PROCEDURE MT+CAS with IV-AP
- PROCEDURE MT+CAS with PO-AP
- PROCEDURE MT+CAT with PO-AP
Study Locations (20)
Florida
- Boca Raton - Baptist Health — Boca Raton
- Delray Medical Center — Delray Beach
- Baptist Health Research Institute — Jacksonville
- University of Florida Health Jacksonville — Jacksonville
- University of Miami School of Medicine — Miami
- Orlando Health, Inc. — Orlando
- University of South Florida — Tampa
- St. Mary's Medical Center — West Palm Beach
California
- Glendale Adventist Medical Center — Glendale
- University of California, Irvine — Irvine
- Pomona Valley — Pomona
- Sutter Institute for Medical Research — Sacramento
- California Pacific Medical Center/Mils Peninsula Medical Center — San Francisco
Illinois
- Ascension/Alexian Brothers Health System — Chicago
- University of Chicago — Chicago
- Northwestern Medicine Central DuPage Hospital — Winfield
Georgia
- Piedmont Healthcare — Atlanta
- WellStar Health System, Inc — Marietta
Alabama
- Mobile Infirmary Medical Center — Mobile
Indiana
- Indiana University Health Methodist Hospital — Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 404 participants |
| Start Date | 2024-05-08 |
| Est. Completion | 2027-05-08 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05611242
The ClinicalTrials.gov registry entry for NCT05611242 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 404 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mercy Health Ohio, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Acute Ischemic Stroke appearing as the primary indexed condition, and to 3 interventions — of which MT+CAS with IV-AP is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05611242 reports 20 study locations spanning 6 distinct geographic areas — top geographies include Florida, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05611242 about?
NCT05611242 is a clinical study titled "Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial". The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke (AIS) from intracranial vessel occlusion (IVO) in the anterior circula...
What is the current status of trial NCT05611242?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 404 participants. The study started on 2024-05-08. Estimated completion is 2027-05-08.
What conditions does trial NCT05611242 study?
This clinical trial studies the following conditions: Acute Ischemic Stroke. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05611242?
The interventions under investigation include: MT+CAS with IV-AP (PROCEDURE), MT+CAS with PO-AP (PROCEDURE), MT+CAT with PO-AP (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05611242?
This trial is sponsored by Mercy Health Ohio, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05611242 being conducted?
This trial has 20 study locations across Alabama, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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