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NCT05045027 · ClinicalTrials.gov registry record · Early Phase 1
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
A Early Phase 1 study of Glioma and Malignant Glioma, sponsored by Jonsson Comprehensive Cancer Center.
- Active
- Registry status
- Early Phase 1
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT05045027: Active Early Phase 1 study of Glioma and Malignant Glioma, sponsored by Jonsson Comprehensive Cancer Center.
NCT05045027 is a Early Phase 1 study of Glioma and Malignant Glioma that is active but no longer recruiting, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 36 participants, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05045027, a Early Phase 1 study of Glioma and Malignant Glioma, is active but no longer recruiting, sponsored by Jonsson Comprehensive Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial constructs and tests a novel multinuclear metabolic magnetic resonance imaging (MRI) sequence in patients with glioma (brain tumor) that is newly diagnosed or has come back (recurrent). This trial aims to develop new diagnostic imaging technology that may bridge gaps between early detection and diagnosis, prognosis, and treatment in brain cancer.
Primary Outcome
Will calculate NaT using standard methodology and normalize it to ocular Na+ concentration, a constant 135 mmol/l. Will then test whether healthy tissue has a coefficient of variance (COV) of \< 10% across all 20 subjects.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Magnetic Resonance Imaging
- PROCEDURE Diagnostic Imaging
Study Locations (1)
California
- UCLA / Jonsson Comprehensive Cancer Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2027-09-10 |
| Phase | Early Phase 1 |
What the registry record for NCT05045027 still lists
NCT05045027 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (83% lower).
The record links to 4 conditions, with Glioma appearing as the primary indexed condition, and to 3 interventions - of which Biospecimen Collection is the first listed.
NCT05045027 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05045027 about?
NCT05045027 is a clinical study titled "Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma". This clinical trial constructs and tests a novel multinuclear metabolic magnetic resonance imaging (MRI) sequence in patients with glioma (brain tumor) that is newly diagnosed or has come back (recurrent). This trial aims to develop new diagnostic imaging technology that may bridge gaps between earl...
What is the current status of trial NCT05045027?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 36 participants. The study started on 2021-09-01. Estimated completion is 2027-09-10.
What conditions does trial NCT05045027 study?
This clinical trial studies the following conditions: Glioma, Malignant Glioma, Recurrent Malignant Glioma, Recurrent Glioma.
What interventions are being tested in trial NCT05045027?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Magnetic Resonance Imaging (PROCEDURE), Diagnostic Imaging (PROCEDURE).
Who is sponsoring clinical trial NCT05045027?
This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05045027 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Glioma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05045027's enrollment target sits among peer trials
36 49th of 87 higher than 39 of 87 other Glioma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glioma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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