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NCT00929006 · ClinicalTrials.gov registry record · Early Phase 1
Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
A Early Phase 1 study of Puberty and Hyperandrogenism, sponsored by University of Virginia.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT00929006: Recruiting Early Phase 1 study of Puberty and Hyperandrogenism, sponsored by University of Virginia.
NCT00929006 is a Early Phase 1 study of Puberty and Hyperandrogenism that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 36 participants, below the 93-participant average among 8 other Puberty trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00929006, a Early Phase 1 study of Puberty and Hyperandrogenism, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is two-fold. (1) We will determine if in mid- to late pubertal girls without hyperandrogenism (HA), progesterone (P4) acutely reduces waking luteinizing hormone (LH) frequency to a greater extent than sleep-associated LH frequency. (2) We will determine if in mid- to late pubertal girls with HA, P4 will acutely suppress waking LH frequency to a lesser degree than it does in girls without HA.
Primary Outcome
LH pulse frequency while awake vs. while asleep pulse frequency
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Micronized progesterone suspension
Study Locations (1)
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2008-06 |
| Est. Completion | 2025-12-01 |
| Phase | Early Phase 1 |
What NCT00929006 shows while recruiting
NCT00929006 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 93-participant average among 8 other Puberty trials with a reported enrollment target (61% lower).
The record links to 2 conditions, with Puberty appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00929006 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT00929006 about?
NCT00929006 is a clinical study titled "Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism". The purpose of this study is two-fold. (1) We will determine if in mid- to late pubertal girls without hyperandrogenism (HA), progesterone (P4) acutely reduces waking luteinizing hormone (LH) frequency to a greater extent than sleep-associated LH frequency. (2) We will determine if in mid- to late p...
What is the current status of trial NCT00929006?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 36 participants. The study started on 2008-06. Estimated completion is 2025-12-01.
What conditions does trial NCT00929006 study?
This clinical trial studies the following conditions: Puberty, Hyperandrogenism.
What interventions are being tested in trial NCT00929006?
The interventions under investigation include: Placebo (DRUG), Micronized progesterone suspension (DRUG).
Who is sponsoring clinical trial NCT00929006?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00929006 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Puberty
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00929006's enrollment target sits among peer trials
36 7th of 8 higher than 2 of 8 other Puberty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Puberty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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