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NCT01891318 · ClinicalTrials.gov registry record · Phase 1

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

A Phase 1 study of Tumors Metastatic to Brain, sponsored by Case Comprehensive Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
36
Enrollment target
2
Study locations

NCT01891318 is a Phase 1 study of Tumors Metastatic to Brain that is actively recruiting participants, run by Case Comprehensive Cancer Center. The registered enrollment target is 36 participants, below the 106-participant average among 4 other Tumors Metastatic to Brain trials with a reported enrollment target (66% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT01891318, a Phase 1 study of Tumors Metastatic to Brain, is actively recruiting participants, sponsored by Case Comprehensive Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
36 participants
Enrollment target
2
Study locations

Study Summary

This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these combined treatments and help determine the best radiosurgery dose. Radiosurgery focuses the x-rays directly to the tumor and cause less damage to the normal tissue in the brain.

Conditions Studied

Interventions

  • PROCEDURE therapeutic conventional surgery
  • RADIATION radiosurgery
  • PROCEDURE quality-of-life assessment

Study Locations (2)

Ohio

  • University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center - Cleveland
  • Cleveland Clinic, Case Comprehensive Cancer Center - Cleveland

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2013-07-03
Est. Completion 2025-12
Phase Phase 1

Sponsor

Case Comprehensive Cancer Center

407 total trials

What the Registry Record Tells You About NCT01891318

The ClinicalTrials.gov registry entry for NCT01891318 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 106-participant average among 4 other Tumors Metastatic to Brain trials with a reported enrollment target (66% lower). The listed sponsor is Case Comprehensive Cancer Center, which has 407 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Tumors Metastatic to Brain appearing as the primary indexed condition, and to 3 interventions - of which therapeutic conventional surgery is the first listed.

NCT01891318 reports 2 study locations spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT01891318 about?

NCT01891318 is a clinical study titled "Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study". This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these combined treatments and help determine the best radiosurgery dose. Radiosurgery focuses the x-rays dir...

What is the current status of trial NCT01891318?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2013-07-03. Estimated completion is 2025-12.

What conditions does trial NCT01891318 study?

This clinical trial studies the following conditions: Tumors Metastatic to Brain.

What interventions are being tested in trial NCT01891318?

The interventions under investigation include: therapeutic conventional surgery (PROCEDURE), radiosurgery (RADIATION), quality-of-life assessment (PROCEDURE).

Who is sponsoring clinical trial NCT01891318?

This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01891318 being conducted?

This trial has 2 study locations across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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