Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 21 of 30

COMPLETED Phase 2

PK/PD Comparison of Guanfacine ER and IR

NCT01904526

COMPLETED NA

iPad Application to Treat Prosodic Deficits in Students With Communication Disorders

NCT01917864

COMPLETED Phase 2

Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence

NCT01847469

COMPLETED NA

Detecting Post-Operative Respiratory Depression in Children

NCT01843933

COMPLETED Phase 4

Attention Training for Opioid-maintained Cocaine Users

NCT01870882

COMPLETED Phase 1

Brain Ketone Metabolism in Type 1 Diabetes

NCT02471040

COMPLETED

Breast Cancer Molecular Analysis Protocol

NCT01855503

COMPLETED NA

Naltrexone for Antipsychotic-Induced Weight Gain

NCT01866098

COMPLETED Phase 1

Ultrasound Biofeedback for Speech Sound Disorders

NCT01905449

COMPLETED

Linking Former Inmates to Primary Care

NCT01863290

COMPLETED Early Phase 1

Characterizing Clinical and Pharmacological Neuroimaging Biomarkers

NCT03842800

COMPLETED

Survey of Smokers Treated in the Emergency Department (ED) on Ownership and Usage of Cell Phones

NCT01820533

COMPLETED NA

Feasibility and Impact of a Decision Rule for Imaging of Emergency Department Patients With Suspected Kidney Stone

NCT01869647

COMPLETED Phase 2

Phase 2 Study of Neoadjuvant Vemurafenib in Melanoma Patients With Untreated Brain Metastases

NCT01781026

COMPLETED Phase 2

Lipiodol as an Imaging Biomarker in Patients With Primary and Metastatic Liver Cancer

NCT01877187

COMPLETED NA

The Momba Mobile Application-based Community

NCT01816945

COMPLETED NA

Text Messaging to Reduce Alcohol Relapse in Liver Transplant Patients

NCT03402256

COMPLETED NA

Patient Navigation for Medicaid Frequent ED Users

NCT01797068

COMPLETED Early Phase 1

Interactive Effects of IV Ethanol and IV Nicotine

NCT01814410

COMPLETED Phase 2

Does Doxazosin Attenuate Stress-induced Smoking and Improve Clinical Outcomes?

NCT01730846

COMPLETED Phase 3

Effect of the LIVESTRONG at the YMCA Exercise Program on Cancer Related Outcomes in Cancer Survivors

NCT02112149

TERMINATED

Study of Stress Hyperglycemia as an Indicator of Diabetes Mellitus

NCT02068989

COMPLETED NA

Virtual Reality Social Cognition Training for Adults With Autism Spectrum Disorders

NCT02139514

COMPLETED NA

Formative Research for an HIV Videogame for Young Black Women

NCT02685410

COMPLETED NA

Integrated Stepped Care for Unhealthy Alcohol Use in HIV

NCT01410123

COMPLETED

Second Young Adult Naturalistic Alcohol Study

NCT01780805

COMPLETED Early Phase 1

Effect of the InsuPatch on Automated Closed-loop Glucose Control in Type 1 Diabetes

NCT01787318

COMPLETED NA

An Interactive Game for HIV Prevention in Early Adolescents

NCT01666496

COMPLETED NA

A Comparison of the Blom Low Profile Voice Inner Cannula and the Passy-Muir One-Way Tracheotomy Tube Speaking Valve on Voice Production, Speech Intelligibility, and Biomechanical Swallowing Behavior

NCT01784224

COMPLETED

SILVER-AMI: Outcomes in Older Persons With Heart Attacks

NCT01755052

COMPLETED NA

A Comparative Study of Occlusive Heat Patch in the Treatment of Warts

NCT01746056

COMPLETED Early Phase 1

Cannabinoids and Cerebellar-Motor Functioning

NCT01853020

COMPLETED

Imaging Extrastriatal Dopamine Release in Tobacco Smokers and Nonsmokers

NCT02348385

TERMINATED NA

A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment

NCT01802515

TERMINATED Phase 2

Investigation of Efficacy of Botulinum Toxin A (Dysport) in Chronic Low Back Pain

NCT02221648

COMPLETED NA

Web-based CBT4CBT for Alcohol

NCT01615497

COMPLETED Phase 1

Impulsivity and Stimulant Administration

NCT01978431

COMPLETED NA

On-line Treatment for Conduct Problems

NCT01822392

COMPLETED Phase 1

Open-Trial of EPI-743 for Adults With Tourette Syndrome

NCT01719523

COMPLETED NA

Neurofeedback for Tourette Syndrome

NCT01702077

COMPLETED NA

Barriers to Use of Remote Monitoring in Patients With Implantable Cardioverter Defibrillators

NCT02361333

COMPLETED NA

Brief Web-Based Alcohol Reduction Intervention for Undergraduates

NCT01694082

TERMINATED Phase 1

An Open Label, International, Multi-centre, Phase I/IIa Study of Lenalidomide (Revlimid) and Romidepsin (Istodax) for Relapsed /Refractory Hodgkin Lymphoma, Mature T-cell Lymphoma and Multiple Myeloma. (RId Study)

NCT01742793

TERMINATED Phase 1

Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction

NCT01978457

COMPLETED Phase 2

Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal

NCT01618656

COMPLETED NA

Performance-based Reinforcement to Enhance Cognitive Remediation Therapy

NCT01633138

COMPLETED NA

Handheld Technology for Speech Development in Students With Autism

NCT01780090

COMPLETED Phase 2

Varenicline Treatment of Alcohol Dependence in Smokers

NCT01553136

COMPLETED NA

Pivotal Response Treatment for Infants At-Risk for Autism Spectrum Disorder

NCT01691066

COMPLETED Early Phase 1

The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

NCT02038595

← Previous Page 21 of 30 Next →

Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.