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NCT01814410 · ClinicalTrials.gov registry record · Early Phase 1
Interactive Effects of IV Ethanol and IV Nicotine
A Early Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 5
- Enrollment target
NCT01814410: Completed Early Phase 1 study, sponsored by Yale University.
NCT01814410 is a Early Phase 1 study that has completed, run by Yale University. The registered enrollment target is 5 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01814410, a Early Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
There are mixed reports on nicotine's effects on ethanol-induced impairment in cognitive performance and behavior in humans. The main objective of this study is to characterize the interactive effects of acute intravenous (IV) ethanol and nicotine administration on cognition and behavior in healthy smokers. The general hypothesis is that nicotine will attenuate the negative effects of ethanol on cognition and subjective stimulant/sedative effects of ethanol.
Primary Outcome
A 14-item scale with 7 items designed to assess stimulant effects associated with the ascending limb of ethanol intoxication and 7 items developed to measure sedative effects associated with the descending limb of ethanol intoxication.
Interventions
- DRUG Intravenous ethanol placebo plus nicotine infusions
- DRUG intravenous ethanol 40mg% plus nicotine infusions
- DRUG intravenous ethanol 100mg% plus nicotine infusions
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2013-02-22 |
| Est. Completion | 2014-06 |
| Phase | Early Phase 1 |
What the finished NCT01814410 record still lists
NCT01814410 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 3 interventions - of which Intravenous ethanol placebo plus nicotine infusions is the first listed.
NCT01814410 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01814410 about?
NCT01814410 is a clinical study titled "Interactive Effects of IV Ethanol and IV Nicotine". There are mixed reports on nicotine's effects on ethanol-induced impairment in cognitive performance and behavior in humans. The main objective of this study is to characterize the interactive effects of acute intravenous (IV) ethanol and nicotine administration on cognition and behavior in healthy ...
What is the current status of trial NCT01814410?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2013-02-22. Estimated completion is 2014-06.
What interventions are being tested in trial NCT01814410?
The interventions under investigation include: Intravenous ethanol placebo plus nicotine infusions (DRUG), intravenous ethanol 40mg% plus nicotine infusions (DRUG), intravenous ethanol 100mg% plus nicotine infusions (DRUG).
Who is sponsoring clinical trial NCT01814410?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01814410's enrollment target sits among peer trials
5 1888th of 2000 higher than 80 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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